PTPN13 Antikörper (AA 801-900)

Produktnummer ABIN714341

Produktdetails anti-PTPN13 Antikörper

Target: PTPN13 (Protein tyrosine Phosphatase, Non-Receptor Type 13 (APO-1/CD95 (Fas)-Associated Phosphatase) (PTPN13))

Bindungsspezifität: AA 801-900

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTPN13 Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FAP1/PTPN13

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-PTPN13 Antikörper (ABIN714341)

Evrard, Lecce, Michelis, Nomura-Kitabayashi, Pandey, Purushothaman, dEscamard, Li, Hadri, Fujitani, Moreno, Benard, Rimmele, Cohain, Mecham, Randolph, Nabel, Hajjar, Fuster, Boehm, Kovacic: "Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability." in: Nature communications, Vol. 7, pp. 11853, (2016) (PubMed).

Details zu PTPN13

Target: PTPN13 (Protein tyrosine Phosphatase, Non-Receptor Type 13 (APO-1/CD95 (Fas)-Associated Phosphatase) (PTPN13))

Andere Bezeichnung: FAP1 (PTPN13 Produkte)

Synonyme: FAP-1 antikoerper, PNP1 antikoerper, PTP-BAS antikoerper, PTP-BL antikoerper, PTP1E antikoerper, PTPL1 antikoerper, PTPLE antikoerper, hPTP1E antikoerper, PTPN13 antikoerper, AI324989 antikoerper, Ptpri antikoerper, RIP antikoerper, Ptp-bl antikoerper, ptp antikoerper, wu:fb50g04 antikoerper, zgc:162319 antikoerper, protein tyrosine phosphatase, non-receptor type 13 antikoerper, tyrosine-protein phosphatase non-receptor type 13 antikoerper, PTPN13 antikoerper, LOC100540743 antikoerper, ptpn13 antikoerper, Ptpn13 antikoerper

Hintergrund:

Synonyms: PNP1, FAP-1, PTP1E, PTPL1, PTPLE, PTP-BL, hPTP1E, PTP-BAS, Tyrosine-protein phosphatase non-receptor type 13, Fas-associated protein-tyrosine phosphatase 1, Protein-tyrosine phosphatase 1E, PTP-E1, hPTPE1, Protein-tyrosine phosphatase PTPL1, PTPN13

Background: Tyrosine phosphatase which regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling (PubMed:15611135). May regulate phosphoinositide 3-kinase (PI3K) signaling through dephosphorylation of PIK3R2 (PubMed:23604317).

Gen-ID: 5783

UniProt: Q12923