PTPN13 Antikörper (AA 250-500)

Produktnummer ABIN6146442

Produktdetails anti-PTPN13 Antikörper

Target: PTPN13 (Protein tyrosine Phosphatase, Non-Receptor Type 13 (APO-1/CD95 (Fas)-Associated Phosphatase) (PTPN13))

Bindungsspezifität: AA 250-500

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTPN13 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)

Sequenz: QDENYFKDIL SDNSGREDSE NTFSPYQFKT SGPEKKPIPG IDVLSKKKIW ASSMDLLCTA DRDFSSGETA TYRRCHPEAV TVRTSTTPRK KEARYSDGSI ALDIFGPQKM DPIYHTRELP TSSAISSALD RIRERQKKLQ VLREAMNVEE PVRRYKTYHG DVFSTSSESP SIISSESDFR QVRRSEASKR FESSSGLPGV DETLSQGQSQ RPSRQYETPF EGNLINQEIM LKRQEEELMQ LQAKMALRQS R

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 250-500 of human PTPN13 (NP_542416.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PTPN13

Target: PTPN13 (Protein tyrosine Phosphatase, Non-Receptor Type 13 (APO-1/CD95 (Fas)-Associated Phosphatase) (PTPN13))

Andere Bezeichnung: PTPN13 (PTPN13 Produkte)

Synonyme: FAP-1 antikoerper, PNP1 antikoerper, PTP-BAS antikoerper, PTP-BL antikoerper, PTP1E antikoerper, PTPL1 antikoerper, PTPLE antikoerper, hPTP1E antikoerper, PTPN13 antikoerper, AI324989 antikoerper, Ptpri antikoerper, RIP antikoerper, Ptp-bl antikoerper, ptp antikoerper, wu:fb50g04 antikoerper, zgc:162319 antikoerper, protein tyrosine phosphatase, non-receptor type 13 antikoerper, tyrosine-protein phosphatase non-receptor type 13 antikoerper, PTPN13 antikoerper, LOC100540743 antikoerper, ptpn13 antikoerper, Ptpn13 antikoerper

Hintergrund: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathways. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.,PTPN13,FAP-1,PNP1,PTP-BAS,PTP-BL,PTP1E,PTPL1,PTPLE,hPTP1E,Cancer,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Cell Cycle,Immunology & Inflammation,IL-6 Receptor Signaling Pathway,PTPN13

Molekulargewicht: 255 kDa/274 kDa/276 kDa/277 kDa

Gen-ID: 5783

UniProt: Q12923