RAD21 Antikörper

Produktnummer ABIN7184040

Produktdetails anti-RAD21 Antikörper

Target: RAD21 (RAD21 Homolog (RAD21))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAD21 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Human, Maus

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from internal of Human RAD21.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:3000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu RAD21

Target: RAD21 (RAD21 Homolog (RAD21))

Andere Bezeichnung: RAD21 (RAD21 Produkte)

Synonyme: rad21 antikoerper, wu:fb55d02 antikoerper, wu:fb93f04 antikoerper, CDLS4 antikoerper, HR21 antikoerper, HRAD21 antikoerper, MCD1 antikoerper, NXP1 antikoerper, SCC1 antikoerper, hHR21 antikoerper, mKIAA0078 antikoerper, hr21 antikoerper, mcd1 antikoerper, nxp-1 antikoerper, nxp1 antikoerper, scc1 antikoerper, xrad21 antikoerper, RAD21 cohesin complex component antikoerper, RAD21 cohesin complex component a antikoerper, RAD21 cohesin complex component L homeolog antikoerper, RAD21 cohesin complex component S homeolog antikoerper, R-spondin 2 antikoerper, RAD21 antikoerper, rad21a antikoerper, rad21.L antikoerper, Rad21 antikoerper, rad21.S antikoerper, RSPO2 antikoerper

Hintergrund:

Background: Cleavable component of the cohesin complex, involved in chromosome cohesion during cell cycle, in DNA repair, and in apoptosis. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At metaphase-anaphase transition, this protein is cleaved by separase/ESPL1 and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Also plays a role in apoptosis, via its cleavage by caspase-3/CASP3 or caspase-7/CASP7 during early steps of apoptosis: the C-terminal 64 kDa cleavage product may act as a nuclear signal to initiate cytoplasmic events involved in the apoptotic pathway.

McKay M.J., Genomics 36:305-315(1996).
Sadano H., Biochem. Biophys. Res. Commun. 267:418-422(2000).
Nomura N., DNA Res. 1:223-229(1994).

Aliases: CDLS4 antibody, Double-strand-break repair protein rad21 homolog antibody, hHR21 antibody, HR21 antibody, HRAD21 antibody, KIAA0078 antibody, MCD1 antibody, Nuclear matrix protein 1 antibody, NXP-1 antibody, NXP1 antibody, Protein involved in DNA double-strand break repair antibody, RAD21 antibody, RAD21 homolog (S. pombe) antibody, RAD21 homolog antibody, RAD21_HUMAN antibody, Scc1 antibody, SCC1 homolog antibody

UniProt: O60216

Pathways: Positive Regulation of Endopeptidase Activity