RAD21 Antikörper (AA 531-631)

Produktnummer ABIN706391

Produktdetails anti-RAD21 Antikörper

Target: RAD21 (RAD21 Homolog (RAD21))

Bindungsspezifität: AA 531-631

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAD21 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Dog,Cow,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Rad2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu RAD21

Target: RAD21 (RAD21 Homolog (RAD21))

Andere Bezeichnung: RAD21 (RAD21 Produkte)

Synonyme: rad21 antikoerper, wu:fb55d02 antikoerper, wu:fb93f04 antikoerper, CDLS4 antikoerper, HR21 antikoerper, HRAD21 antikoerper, MCD1 antikoerper, NXP1 antikoerper, SCC1 antikoerper, hHR21 antikoerper, mKIAA0078 antikoerper, hr21 antikoerper, mcd1 antikoerper, nxp-1 antikoerper, nxp1 antikoerper, scc1 antikoerper, xrad21 antikoerper, RAD21 cohesin complex component antikoerper, RAD21 cohesin complex component a antikoerper, RAD21 cohesin complex component L homeolog antikoerper, RAD21 cohesin complex component S homeolog antikoerper, R-spondin 2 antikoerper, RAD21 antikoerper, rad21a antikoerper, rad21.L antikoerper, Rad21 antikoerper, rad21.S antikoerper, RSPO2 antikoerper

Hintergrund:

Synonyms: HR21, MCD1, NXP1, SCC1, CDLS4, hHR21, HRAD21, Double-strand-break repair protein rad21 homolog, Nuclear matrix protein 1, NXP-1, SCC1 homolog, RAD21, KIAA0078

Background: Cleavable component of the cohesin complex, involved in chromosome cohesion during cell cycle, in DNA repair, and in apoptosis. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At metaphase-anaphase transition, this protein is cleaved by separase/ESPL1 and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Also plays a role in apoptosis, via its cleavage by caspase-3/CASP3 or caspase-7/CASP7 during early steps of apoptosis: the C-terminal 64 kDa cleavage product may act as a nuclear signal to initiate cytoplasmic events involved in the apoptotic pathway.

Gen-ID: 5885

UniProt: O60216

Pathways: Positive Regulation of Endopeptidase Activity