RAD21 Antikörper (Center)

Produktnummer ABIN2856242

Produktdetails anti-RAD21 Antikörper

Target: RAD21 (RAD21 Homolog (RAD21))

Bindungsspezifität: Center

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAD21 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Produktmerkmale: Rabbit Polyclonal antibody to RAD21 (RAD21 homolog (S. pombe))
RAD21 antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human RAD21. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Immunoprecipitation 1:100-1:500* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Immunoprecipitation1:100-1:500* Western blot1:500-1:3000*

Kommentare:

Positive Control: K562 , THP-1 , HL-60 , NIH-3T3 , JC , BCL-1

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS, 20 % Glycerol ( pH 7). 0.025 % ProClin 300 was added as a preservative.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-RAD21 Antikörper (ABIN2856242)

Ochiai, Hayashi, Umeda, Yoshimura, Harada, Shimizu, Nakano, Saitoh, Liu, Yamamoto, Okamura, Ohkawa, Kimura, Nikaido: "Genome-wide kinetic properties of transcriptional bursting in mouse embryonic stem cells." in: Science advances, Vol. 6, Issue 25, pp. eaaz6699, (2020) (PubMed).

Details zu RAD21

Target: RAD21 (RAD21 Homolog (RAD21))

Andere Bezeichnung: RAD21 (RAD21 Produkte)

Synonyme: rad21 antikoerper, wu:fb55d02 antikoerper, wu:fb93f04 antikoerper, CDLS4 antikoerper, HR21 antikoerper, HRAD21 antikoerper, MCD1 antikoerper, NXP1 antikoerper, SCC1 antikoerper, hHR21 antikoerper, mKIAA0078 antikoerper, hr21 antikoerper, mcd1 antikoerper, nxp-1 antikoerper, nxp1 antikoerper, scc1 antikoerper, xrad21 antikoerper, RAD21 cohesin complex component antikoerper, RAD21 cohesin complex component a antikoerper, RAD21 cohesin complex component L homeolog antikoerper, RAD21 cohesin complex component S homeolog antikoerper, R-spondin 2 antikoerper, RAD21 antikoerper, rad21a antikoerper, rad21.L antikoerper, Rad21 antikoerper, rad21.S antikoerper, RSPO2 antikoerper

Hintergrund: The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells.

Cellular Localization: Nucleus

Molekulargewicht: 72 kDa

Gen-ID: 5885

Pathways: Positive Regulation of Endopeptidase Activity