ATG7 Antikörper (AA 386-676) (FITC)

Produktnummer ABIN7343896

Produktdetails anti-ATG7 Antikörper (FITC)

Target: ATG7 (ATG7 Autophagy Related 7 (ATG7))

Bindungsspezifität: AA 386-676

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATG7 Antikörper ist konjugiert mit FITC

Applikation: Bitte anfragen

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Ubiquitin-like modifier-activating enzyme ATG7 protein (386-676AA)

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ATG7

Target: ATG7 (ATG7 Autophagy Related 7 (ATG7))

Andere Bezeichnung: ATG7 (ATG7 Produkte)

Synonyme: APG7-LIKE antikoerper, APG7L antikoerper, GSA7 antikoerper, D8 antikoerper, UBA1B antikoerper, UBE1L antikoerper, UBE2 antikoerper, Ube1l antikoerper, 1300004C08Rik antikoerper, AO090001000744 antikoerper, atg7 antikoerper, 1810013K23Rik antikoerper, Agp7 antikoerper, Apg7l antikoerper, Atg7l antikoerper, ATAPG7 antikoerper, ATATG7 antikoerper, ATG7 antikoerper, AUTOPHAGY 7 antikoerper, AUTOPHAGY-RELATED 7 antikoerper, K15I22.10 antikoerper, K15I22_10 antikoerper, autophagy related 7 antikoerper, ubiquitin like modifier activating enzyme 7 antikoerper, ubiquitin-like modifier activating enzyme 7 antikoerper, autophagy-related protein 7 antikoerper, Autophagy-related protein 7 antikoerper, Apg7p antikoerper, ThiF family protein antikoerper, ubiquitin-like conjugating enzyme Atg7 antikoerper, ATG7 antikoerper, UBA7 antikoerper, Uba7 antikoerper, ANI_1_3368024 antikoerper, AOR_1_1338164 antikoerper, PTRG_02236 antikoerper, PAAG_00287 antikoerper, PITG_12537 antikoerper, atg7 antikoerper, Atg7 antikoerper, APG7 antikoerper

Hintergrund:

Background: E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Modulates p53/TP53 activity to regulate cell cycle and survival during metabolic stress. Plays also a key role in the maintenance of axonal homeostasis, the prevention of axonal degeneration, the maintenance of hematopoietic stem cells, the formation of Paneth cell granules, as well as in adipose differentiation.

Aliases: 1810013K23Rik antibody, Apg 7 antibody, APG7 autophagy 7 like antibody, APG7 autophagy 7-like (S. cerevisiae) antibody, APG7 like antibody, APG7, S. cerevisiae, homolog of antibody, APG7-like antibody, APG7L antibody, ATG 7 antibody, ATG12-activating enzyme E1 ATG7 antibody, ATG7 antibody, ATG7 autophagy related 7 homolog (S. cerevisiae) antibody, ATG7 autophagy related 7 homolog antibody, ATG7_HUMAN antibody, Atg7l antibody, Autophagy 7, S. cerevisiae, homolog of antibody, Autophagy related protein 7 antibody, Autophagy-related 7 (yeast) antibody, Autophagy-related protein 7 antibody, DKFZp434N0735 antibody, GSA 7 antibody, GSA7 antibody, hAGP7 antibody, Ubiquitin activating enzyme E1 like protein antibody, Ubiquitin-activating enzyme E1-like protein antibody, Ubiquitin-like modifier-activating enzyme ATG7 antibody

UniProt: O95352

Pathways: Response to Water Deprivation, Autophagie