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ATG7 Antikörper (AA 22-51)

ATG7 Reaktivität: Human, Maus WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3030039
  • Target Alle ATG7 Antikörper anzeigen
    ATG7 (ATG7 Autophagy Related 7 (ATG7))
    Bindungsspezifität
    • 22
    • 16
    • 15
    • 9
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 22-51
    Reaktivität
    • 125
    • 39
    • 28
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 113
    • 13
    • 2
    Kaninchen
    Klonalität
    • 106
    • 22
    Polyklonal
    Konjugat
    • 63
    • 9
    • 9
    • 8
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ATG7 Antikörper ist unkonjugiert
    Applikation
    • 107
    • 63
    • 46
    • 26
    • 18
    • 15
    • 14
    • 14
    • 13
    • 9
    • 5
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Kreuzreaktivität (Details)
    Expected species reactivity: Rat
    Aufreinigung
    Antigen affinity purified
    Immunogen
    A portion of amino acids 22-51 from the human protein was used as the immunogen for this ATG7 antibody.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product ATG7 Primärantikörper
  • Applikationshinweise
    Titration of the ATG7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot the ATG7 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    ATG7 (ATG7 Autophagy Related 7 (ATG7))
    Andere Bezeichnung
    ATG7 (ATG7 Produkte)
    Synonyme
    APG7-LIKE antikoerper, APG7L antikoerper, GSA7 antikoerper, D8 antikoerper, UBA1B antikoerper, UBE1L antikoerper, UBE2 antikoerper, Ube1l antikoerper, 1300004C08Rik antikoerper, AO090001000744 antikoerper, atg7 antikoerper, 1810013K23Rik antikoerper, Agp7 antikoerper, Apg7l antikoerper, Atg7l antikoerper, ATAPG7 antikoerper, ATATG7 antikoerper, ATG7 antikoerper, AUTOPHAGY 7 antikoerper, AUTOPHAGY-RELATED 7 antikoerper, K15I22.10 antikoerper, K15I22_10 antikoerper, autophagy related 7 antikoerper, ubiquitin like modifier activating enzyme 7 antikoerper, ubiquitin-like modifier activating enzyme 7 antikoerper, autophagy-related protein 7 antikoerper, Autophagy-related protein 7 antikoerper, Apg7p antikoerper, ThiF family protein antikoerper, ubiquitin-like conjugating enzyme Atg7 antikoerper, ATG7 antikoerper, UBA7 antikoerper, Uba7 antikoerper, ANI_1_3368024 antikoerper, AOR_1_1338164 antikoerper, PTRG_02236 antikoerper, PAAG_00287 antikoerper, PITG_12537 antikoerper, atg7 antikoerper, Atg7 antikoerper, APG7 antikoerper
    Hintergrund
    ATG7 is an E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Modulates p53/TP53 activity to regulate cell cycle and survival during metabolic stress. Plays also a key role in the maintenance of axonal homeostasis, the prevention of axonal degeneration, the maintenance of hematopoietic stem cells, the formation of Paneth cell granules, as well as in adipose differentiation. [UniProt]
    UniProt
    O95352
    Pathways
    Response to Water Deprivation, Autophagie
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