TEAD1 Antikörper (AA 135-215)

Produktnummer ABIN7172758

Produktdetails anti-TEAD1 Antikörper

Target: TEAD1 (TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1))

Bindungsspezifität: AA 135-215

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TEAD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Transcriptional enhancer factor TEF-1 protein (135-215AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:500, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu TEAD1

Target: TEAD1 (TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1))

Andere Bezeichnung: TEAD1 (TEAD1 Produkte)

Synonyme: tead1 antikoerper, zgc:63696 antikoerper, TEAD1 antikoerper, xtead1 antikoerper, 2610024B07Rik antikoerper, B230114H05Rik antikoerper, Gtrgeo5 antikoerper, TEAD-1 antikoerper, TEF-1 antikoerper, Tcf13 antikoerper, mTEF-1 antikoerper, AA antikoerper, NTEF-1 antikoerper, REF1 antikoerper, TCF-13 antikoerper, TCF13 antikoerper, XNTEF-1 antikoerper, xlNTEF-1 antikoerper, TEA domain family member 1a antikoerper, TEA domain transcription factor 1 antikoerper, TEA domain family member 1 (SV40 transcriptional enhancer factor) antikoerper, TEA domain family member 1 antikoerper, TEA domain family member 1 (SV40 transcriptional enhancer factor) S homeolog antikoerper, TEA domain family member 1b antikoerper, tead1a antikoerper, TEAD1 antikoerper, tead1 antikoerper, Tead1 antikoerper, tead1.S antikoerper, tead1b antikoerper

Hintergrund:

Background: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and cooperatively to the SPH and GT-IIC \\\'enhansons\\\' (5\\\'-GTGGAATGT-3\\\') and activates transcription in vivo in a cell-specific manner. The activation function appears to be mediated by a limiting cell-specific transcriptional intermediary factor (TIF). Involved in cardiac development. Binds to the M-CAT motif.

Aliases: AA antibody, Atrophia areata peripapillary chorioretinal degeneration antibody, NTEF 1 antibody, NTEF-1 antibody, NTEF1 antibody, Protein GT IIC antibody, Protein GT-IIC antibody, REF 1 antibody, REF1 antibody, SV40 transcriptional enhancer factor antibody, TCF 13 antibody, TCF-13 antibody, TCF13 antibody, TEA domain family member antibody, TEA domain family member 1 (SV40 transcriptional enhancer factor) antibody, TEA domain family member 1 antibody, TEAD 1 antibody, TEAD 1 protein antibody, TEAD-1 antibody, TEAD1 antibody, TEAD1 protein antibody, TEAD1_HUMAN antibody, TEF 1 antibody, TEF1 antibody, Transcription factor 13 (SV40 transcriptional enhancer factor) antibody, Transcription factor 13 antibody, Transcriptional enhancer factor 1 antibody, Transcriptional enhancer factor TEF-1 antibody, Transcriptional enhancer factor TEF1 antibody

UniProt: P28347

Pathways: Regulation of Lipid Metabolism by PPARalpha