DIO3 Antikörper (AA 50-115)

Produktnummer ABIN7172188

Produktdetails anti-DIO3 Antikörper

Target: DIO3 (Deiodinase, Iodothyronine, Type III (DIO3))

Bindungsspezifität: AA 50-115

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DIO3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Thyroxine 5-deiodinase protein (50-115AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu DIO3

Target: DIO3 (Deiodinase, Iodothyronine, Type III (DIO3))

Andere Bezeichnung: DIO3 (DIO3 Produkte)

Synonyme: 5DIII antikoerper, DIOIII antikoerper, txdi3 antikoerper, dioiii antikoerper, XL-15 antikoerper, itdi3 antikoerper, D3 antikoerper, TXDI3 antikoerper, iodothyronine deiodinase 3 antikoerper, deiodinase, iodothyronine, type 3 antikoerper, deiodinase, iodothyronine, type III antikoerper, deiodinase, iodothyronine type III antikoerper, deiodinase, iodothyronine, type 3 L homeolog antikoerper, DIO3 antikoerper, dio3 antikoerper, Dio3 antikoerper, dio3.L antikoerper

Hintergrund:

Background: Responsible for the deiodination of T4 (3,5,3\',5\'-tetraiodothyronine) into RT3 (3,3\',5\'-triiodothyronine) and of T3 (3,5,3\'-triiodothyronine) into T2 (3,3\'-diiodothyronine). RT3 and T2 are inactive metabolites. May play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones. Can regulate circulating fetal thyroid hormone concentrations throughout gestation. Essential role for regulation of thyroid hormone inactivation during embryological development.

Aliases: 5DIII antibody, D3 antibody, Deiodinase iodothyronine type 3 antibody, Deiodinase iodothyronine type III antibody, Dio 3 antibody, Dio3 antibody, DIOIII antibody, IOD3_HUMAN antibody, Iodothyronine deiodinase placental type antibody, MGC124117 antibody, MGC124118 antibody, Thyroxine deiodinase type III antibody, Thyroxine deiodinase type III (selenoprotein) antibody, TXDI3 antibody, Type 3 DI antibody, Type 3 iodothyronine selenodeiodinase antibody, Type III 5' deiodinase antibody, Type III iodothyronine deiodinase antibody, Type-III 5''-deiodinase antibody

UniProt: P55073

Pathways: Hormone Activity