SKA3 Antikörper (AA 101-195) (Biotin)

Produktnummer ABIN7170596

Produktdetails anti-SKA3 Antikörper (Biotin)

Target: SKA3 (Spindle and Kinetochore Associated Complex Subunit 3 (SKA3))

Bindungsspezifität: AA 101-195

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SKA3 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Spindle and kinetochore-associated protein 3 protein (101-195AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SKA3

Target: SKA3 (Spindle and Kinetochore Associated Complex Subunit 3 (SKA3))

Andere Bezeichnung: SKA3 (SKA3 Produkte)

Synonyme: C13orf3 antikoerper, RAMA1 antikoerper, RGD1307201 antikoerper, C12H13ORF3 antikoerper, fc23d11 antikoerper, si:rp71-68n21.13 antikoerper, wu:fc23d11 antikoerper, rama1 antikoerper, F630043A04Rik antikoerper, spindle and kinetochore associated complex subunit 3 antikoerper, spindle and kinetochore associated complex subunit 3 L homeolog antikoerper, SKA3 antikoerper, Ska3 antikoerper, ska3 antikoerper, ska3.L antikoerper

Hintergrund:

Background: Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation (PubMed:19289083, PubMed:19360002, PubMed:23085020). The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies (PubMed:19289083, PubMed:19360002). The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner (PubMed:19289083). In the complex, it mediates the microtubule-stimulated oligomerization (PubMed:19289083). Affinity for microtubules is synergistically enhanced in the presence of the ndc-80 complex and may allow the ndc-80 complex to track depolymerizing microtubules (PubMed:23085020).

Aliases: C13orf3 antibody, RAMA1 antibody, SKA3 antibody, SKA3_HUMAN antibody, Spindle and kinetochore associated complex subunit 3 antibody, Spindle and kinetochore-associated protein 3 antibody

UniProt: Q8IX90