PPP1CC Antikörper (Catalytic Subunit)

Produktnummer ABIN7169312

Produktdetails anti-PPP1CC Antikörper

Target: PPP1CC (Protein Phosphatase 1, Catalytic Subunit, gamma Isoform (PPP1CC))

Bindungsspezifität: AA 151-323, Catalytic Subunit

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPP1CC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human, Maus

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Serine/threonine-protein phosphatase PP1-gamma catalytic subunit protein (151-323AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:2000-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PPP1CC

Target: PPP1CC (Protein Phosphatase 1, Catalytic Subunit, gamma Isoform (PPP1CC))

Andere Bezeichnung: PPP1CC (PPP1CC Produkte)

Synonyme: PP-1G antikoerper, ppp1g antikoerper, PP1 antikoerper, dis2m1 antikoerper, fe06g11 antikoerper, fi22e08 antikoerper, wu:fe06g11 antikoerper, wu:fi22e08 antikoerper, PP1C antikoerper, PPP1G antikoerper, Ppp1cc1 antikoerper, ppp1cc-a antikoerper, protein phosphatase 1, catalytic subunit, gamma isozyme antikoerper, protein phosphatase 1, catalytic subunit, gamma isoform antikoerper, protein phosphatase 1 catalytic subunit gamma antikoerper, protein phosphatase 1, catalytic subunit, gamma isozyme L homeolog antikoerper, ppp1cc antikoerper, Ppp1cc antikoerper, PPP1CC antikoerper, ppp1cc.L antikoerper

Hintergrund:

Background: Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Dephosphorylates RPS6KB1. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca(2+)/calmodulin dependent protein kinase II. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E. Dephosphorylates the \\\'Ser-418\\\' residue of FOXP3 in regulatory T-cells (Treg) from patients with rheumatoid arthritis, thereby inactivating FOXP3 and rendering Treg cells functionally defective (PubMed:23396208).

Aliases: PP 1G antibody, PP-1G antibody, PP1C antibody, PP1G antibody, PP1G_HUMAN antibody, PP1gamma antibody, PPP 1G antibody, PPP1CC antibody, PPP1G antibody, Protein phosphatase 1, catalytic subunit, gamma isozyme antibody, Protein phosphatase 1C catalytic subunit antibody, Serine/threonine phosphatase 1 gamma antibody, Serine/threonine protein phosphatase PP1 gamma catalytic subunit antibody, Serine/threonine-protein phosphatase PP1-gamma catalytic subunit antibody

UniProt: P36873

Pathways: Cellular Glucan Metabolic Process, Lipid Metabolism