PPP1CC Antikörper (Center)

Produktnummer ABIN2856137

Produktdetails anti-PPP1CC Antikörper

Target: PPP1CC (Protein Phosphatase 1, Catalytic Subunit, gamma Isoform (PPP1CC))

Bindungsspezifität: Center

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPP1CC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)

Kreuzreaktivität: Ratte (Rattus), Xenopus laevis, Xenopus tropicalis, Huhn, Rhesusaffen, Rind (Kuh)

Kreuzreaktivität (Details): Rat (100 %), Xenopus laevis (100 %), Xenopus Tropicalis (100 %), Chicken (100 %), Rhesus Monkey (100 %), Bovine (100 %)

Produktmerkmale: Rabbit Polyclonal antibody to PP1C gamma (protein phosphatase 1, catalytic subunit, gamma isozyme)
PP1C gamma antibody [N1C2]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PP1C gamma. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Kommentare:

Positive Control: 293T , A431 , HeLa , HepG2 , Molt-4 , Raji , NIH-3T3

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-PPP1CC Antikörper (ABIN2856137)

Kenney, Genheden, Moon, Wang, Foster, Proud: "Eukaryotic elongation factor 2 kinase regulates the synthesis of microtubule-related proteins in neurons." in: Journal of neurochemistry, Vol. 136, Issue 2, pp. 276-84, (2016) (PubMed).

Wei, Ngo, Wu, Lee: "Phosphorylation of the Ndc80 complex protein, HEC1, by Nek2 kinase modulates chromosome alignment and signaling of the spindle assembly checkpoint." in: Molecular biology of the cell, Vol. 22, Issue 19, pp. 3584-94, (2012) (PubMed).

Details zu PPP1CC

Target: PPP1CC (Protein Phosphatase 1, Catalytic Subunit, gamma Isoform (PPP1CC))

Andere Bezeichnung: PP1C gamma (PPP1CC Produkte)

Synonyme: PP-1G antikoerper, ppp1g antikoerper, PP1 antikoerper, dis2m1 antikoerper, fe06g11 antikoerper, fi22e08 antikoerper, wu:fe06g11 antikoerper, wu:fi22e08 antikoerper, PP1C antikoerper, PPP1G antikoerper, Ppp1cc1 antikoerper, ppp1cc-a antikoerper, protein phosphatase 1, catalytic subunit, gamma isozyme antikoerper, protein phosphatase 1, catalytic subunit, gamma isoform antikoerper, protein phosphatase 1 catalytic subunit gamma antikoerper, protein phosphatase 1, catalytic subunit, gamma isozyme L homeolog antikoerper, ppp1cc antikoerper, Ppp1cc antikoerper, PPP1CC antikoerper, ppp1cc.L antikoerper

Hintergrund: Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca(2+)/calmodulin dependent protein kinase II.

Molekulargewicht: 37 kDa

Gen-ID: 5501

Pathways: Cellular Glucan Metabolic Process, Lipid Metabolism