PPP2R4 Antikörper (AA 1-250)

Produktnummer ABIN7169262

Produktdetails anti-PPP2R4 Antikörper

Target: PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4))

Bindungsspezifität: AA 1-250

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPP2R4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Serine/threonine-protein phosphatase 2A activator protein (1-250AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:1000-1:2000, IF:1:200-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PPP2R4

Target: PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4))

Andere Bezeichnung: PTPA (PPP2R4 Produkte)

Synonyme: PP2A antikoerper, PR53 antikoerper, PTPA antikoerper, 2610042B21Rik antikoerper, C77440 antikoerper, N28142 antikoerper, PTPRA antikoerper, Ppp2r4 antikoerper, fc23d07 antikoerper, ppp2r4 antikoerper, wu:fc23d07 antikoerper, zgc:92766 antikoerper, pp2a antikoerper, ppp2r4.L antikoerper, pr53 antikoerper, ptpa antikoerper, protein phosphatase 2 phosphatase activator antikoerper, protein phosphatase 2 protein activator antikoerper, protein phosphatase 2 phosphatase activator L homeolog antikoerper, PTPA antikoerper, Ptpa antikoerper, ptpa antikoerper, ptpa.L antikoerper

Hintergrund:

Background: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for serine/threonine-protein phosphatase 2A (PP2A) modulating its activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a proposed direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2A(i)) in presence of ATP and Mg(2+) (By similarity). Reversibly stimulates the variable phosphotyrosyl phosphatase activity of PP2A core heterodimer PP2A(D) in presence of ATP and Mg(2+) (in vitro). The phosphotyrosyl phosphatase activity is dependent of an ATPase activity of the PP2A(D):PPP2R4 complex. Is involved in apoptosis, the function appears to be independent from PP2A.

Aliases: subunit B'' antibody, KIAA0044 antibody, MGC2184 antibody, Phosphotyrosyl phosphatase activator antibody, PP2A antibody, PP2A phosphatase activator antibody, PP2A subunit B' antibody, PP2A subunit B' isoform PR53 antibody, PP2A subunit B' PR53 isoform antibody, PPP2R4 antibody, PR53 antibody, PR53 isoform antibody, Protein phosphatase 2, regulatory subunit B-prime antibody, Protein phosphatase 2A activator regulatory subunit 4 antibody, Protein phosphatase 2A regulatory subunit B' (PR 53) antibody, PTPA antibody, PTPA_HUMAN antibody, Serine/threonine protein phosphatase 2A regulatory subunit B' antibody, Serine/threonine-protein phosphatase 2A activator antibody, Serine/threonine-protein phosphatase 2A regulatory subunit 4 antibody, Serine/threonine-protein phosphatase 2A regulatory subunit B'' antibody

UniProt: Q15257

Pathways: PI3K-Akt Signalweg, M Phase, Hepatitis C, Toll-Like Receptors Cascades