PPM1D Antikörper (AA 1-250)

Produktnummer ABIN7165942

Produktdetails anti-PPM1D Antikörper

Target: PPM1D (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D))

Bindungsspezifität: AA 1-250

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPM1D Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human, Ratte

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Protein phosphatase 1D protein (1-250AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PPM1D

Target: PPM1D (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D))

Andere Bezeichnung: PPM1D (PPM1D Produkte)

Synonyme: PP2C-DELTA antikoerper, WIP1 antikoerper, AV338790 antikoerper, Wip1 antikoerper, zgc:103518 antikoerper, ppm1d antikoerper, wu:fj44c08 antikoerper, zgc:55836 antikoerper, zgc:77316 antikoerper, protein phosphatase, Mg2+/Mn2+ dependent 1D antikoerper, protein phosphatase 1D magnesium-dependent, delta isoform antikoerper, protein phosphatase, Mg2+/Mn2+ dependent, 1D antikoerper, protein phosphatase, Mg2+/Mn2+ dependent, 1Db antikoerper, protein phosphatase, Mg2+/Mn2+ dependent 1D L homeolog antikoerper, protein phosphatase, Mg2+/Mn2+ dependent, 1Da antikoerper, PPM1D antikoerper, Ppm1d antikoerper, ppm1db antikoerper, ppm1d.L antikoerper, ppm1da antikoerper

Hintergrund:

Background: Required for the relief of p53-dependent checkpoint mediated cell cycle arrest. Binds to and dephosphorylates \\\'Ser-15\\\' of TP53 and \\\'Ser-345\\\' of CHEK1 which contributes to the functional inactivation of these proteins. Mediates MAPK14 dephosphorylation and inactivation (PubMed:21283629).

Aliases: EC 3.1.3.16 antibody, p53 induced protein phosphatase 1 antibody, p53-induced protein phosphatase 1 antibody, PP2C delta antibody, PP2C-delta antibody, PP2CD antibody, Ppm1d antibody, PPM1D_HUMAN antibody, Protein phosphatase 1D antibody, protein phosphatase 1D magnesium-dependent delta isoform antibody, Protein phosphatase 2C delta isoform antibody, Protein phosphatase 2C isoform delta antibody, Protein phosphatase magnesium dependent 1 delta antibody, Protein phosphatase magnesium-dependent 1 delta antibody, Protein phosphatase Mg2+/Mn2+ dependent 1D antibody, Protein phosphatase Wip1 antibody, Wild type p53 induced phosphatase 1 antibody, WIP 1 antibody, WIP1 antibody

UniProt: O15297

Pathways: p53 Signalweg, Zellzyklus