PPM1D Antikörper
Kurzübersicht für PPM1D Antikörper (ABIN7506006)
Target
Alle PPM1D Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-PPM1D Purified
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Produktmerkmale
- The mouse monoclonal antibody 7E11/C5 recognizes an epitope within the sequence FTNEDELYNLLTDSP of PPM1D, a protein phosphatase, which contributes to development of some carcinomas.
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Aufreinigung
- Purified by protein-A affinity chromatography.
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Immunogen
- Purified human PPM1D
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Isotyp
- IgG1
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anti-Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D) (AA 201-300) antibody
PPM1D Reaktivität: Human WB, ELISA, IF (cc), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D) (AA 496-605) antibodyPPM1D Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 4D1 unconjugated
anti-Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D) (AA 1-250) antibodyPPM1D Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D) (AA 183-212) antibodyPPM1D Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB33957 unconjugated
anti-Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D) (C-Term) antibodyPPM1D Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D) (AA 571-602), (C-Term) antibodyPPM1D Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB6018 unconjugated
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Applikationshinweise
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Western blotting: Recommended dilution: 1-2 μg/mL.
Flow cytometry: Recommended dilution: 1-5 μg/mL. Intracellular staining. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Do not freeze
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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- PPM1D (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D))
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Andere Bezeichnung
- PPM1D
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Hintergrund
- Protein phosphatase, Mg2+/Mn2+ dependent 1D,PPM1D is a Mg2+/Mn2+ dependent protein phosphatase 1D with inducible expression in response to various types of environmental stress. This expression is p53-dependent, and subsequently PPM1D negatively regulates the p53-mediated transcription, thus it suppresses the apoptosis. PPM1D contributes to development of carcinomas, and seems to be a promissing therapeutic target. Amplification of PPM1D is associated with breast cancer.,WIP1, Protein phosphatase 1D, JDVS, WIP1, IDDGIP
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Gen-ID
- 8493
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UniProt
- O15297
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Pathways
- p53 Signalweg, Zellzyklus
Target
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