PIK3R6 Antikörper (Regulatory Subunit 6) (HRP)

Produktnummer ABIN7163302

Produktdetails anti-PIK3R6 Antikörper (HRP)

Target: PIK3R6 (Phosphoinositide-3-Kinase, Regulatory Subunit 6 (PIK3R6))

Bindungsspezifität: AA 566-667, Regulatory Subunit 6

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIK3R6 Antikörper ist konjugiert mit HRP

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Phosphoinositide 3-kinase regulatory subunit 6 protein (566-667AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PIK3R6

Target: PIK3R6 (Phosphoinositide-3-Kinase, Regulatory Subunit 6 (PIK3R6))

Andere Bezeichnung: PIK3R6 (PIK3R6 Produkte)

Synonyme: C17orf38 antikoerper, HsT41028 antikoerper, p84 antikoerper, p84 PIKAP antikoerper, p87(PIKAP) antikoerper, p87PIKAP antikoerper, BB220380 antikoerper, RGD1560850 antikoerper, phosphoinositide-3-kinase regulatory subunit 6 antikoerper, phosphoinositide-3-kinase regulatory subunit 5 antikoerper, phosphoinositide-3-kinase, regulatory subunit 6 antikoerper, PIK3R6 antikoerper, Pik3r6 antikoerper

Hintergrund:

Background: Regulatory subunit of the PI3K gamma complex. Acts as an adapter to drive activation of PIK3CG by beta-gamma G protein dimers. The PIK3CG:PIK3R6 heterodimer is much less sensitive to beta-gamma G protein dimers than PIK3CG:PIK3R5 and its membrane recruitment and beta-gamma G protein dimer-dependent activation requires HRAS bound to PIK3CG. Recruits of the PI3K gamma complex to a PDE3B:RAPGEF3 signaling complex involved in angiogenesis, signaling seems to involve RRAS.

Aliases: C17orf38 antibody, Chromosome 17 open reading frame 38 antibody, HsT41028 antibody, p84 PI3K adapter protein antibody, p84 PIKAP antibody, p87 phosphoinositide 3-kinase gamma (PI3Kg) adapter protein antibody, p87 PI3K adapter protein antibody, p87PIKAP antibody, Phosphatidylinositol 3-kinase, regulatory subunit 6 antibody, Phosphoinositide 3-kinase gamma adapter protein of 87 kDa antibody, Phosphoinositide 3-kinase regulatory subunit 6 antibody, PI3Kgamma adapter protein of 87 kDa antibody, PI3R6_HUMAN antibody, PIK3R6 antibody

UniProt: Q5UE93

Pathways: PI3K-Akt Signalweg, Inositol Metabolic Process