PIK3R6 Antikörper (C-Term)

Produktnummer ABIN6264219

Produktdetails anti-PIK3R6 Antikörper

Target: PIK3R6 (Phosphoinositide-3-Kinase, Regulatory Subunit 6 (PIK3R6))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIK3R6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Spezifität: PIK3R6 Antibody detects endogenous levels of total PIK3R6.

Homologie: Pig,Bovine,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PIK3R6, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu PIK3R6

Target: PIK3R6 (Phosphoinositide-3-Kinase, Regulatory Subunit 6 (PIK3R6))

Andere Bezeichnung: PIK3R6 (PIK3R6 Produkte)

Synonyme: C17orf38 antikoerper, HsT41028 antikoerper, p84 antikoerper, p84 PIKAP antikoerper, p87(PIKAP) antikoerper, p87PIKAP antikoerper, BB220380 antikoerper, RGD1560850 antikoerper, phosphoinositide-3-kinase regulatory subunit 6 antikoerper, phosphoinositide-3-kinase regulatory subunit 5 antikoerper, phosphoinositide-3-kinase, regulatory subunit 6 antikoerper, PIK3R6 antikoerper, Pik3r6 antikoerper

Hintergrund:

Description: Regulatory subunit of the PI3K gamma complex. Acts as an adapter to drive activation of PIK3CG by beta-gamma G protein dimers. The PIK3CG:PIK3R6 heterodimer is much less sensitive to beta-gamma G protein dimers than PIK3CG:PIK3R5 and its membrane recruitment and beta-gamma G protein dimer-dependent activation requires HRAS bound to PIK3CG. Recruits of the PI3K gamma complex to a PDE3B:RAPGEF3 signaling complex involved in angiogenesis, signaling seems to involve RRAS.

Gene: PIK3R6

Molekulargewicht: 84 kDa

Gen-ID: 146850

UniProt: Q5UE93

Pathways: PI3K-Akt Signalweg, Inositol Metabolic Process