ARPC2 Antikörper (AA 1-250) (HRP)

Produktnummer ABIN7143088

Produktdetails anti-ARPC2 Antikörper (HRP)

Target: ARPC2 (Actin Related Protein 2/3 Complex, Subunit 2, 34kDa (ARPC2))

Bindungsspezifität: AA 1-250

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARPC2 Antikörper ist konjugiert mit HRP

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Actin-related protein 2/3 complex subunit 2 protein (1-250AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ARPC2

Target: ARPC2 (Actin Related Protein 2/3 Complex, Subunit 2, 34kDa (ARPC2))

Andere Bezeichnung: ARPC2 (ARPC2 Produkte)

Synonyme: arc34 antikoerper, p34-arc antikoerper, pnas-139 antikoerper, pro2446 antikoerper, Arpc2 antikoerper, Arc-p34 antikoerper, 2210023N03Rik antikoerper, 34kDa antikoerper, p34-Arc antikoerper, fk84a07 antikoerper, wu:fa22f07 antikoerper, wu:fk84a07 antikoerper, zgc:77769 antikoerper, ARC34 antikoerper, PNAS-139 antikoerper, actin related protein 2/3 complex subunit 2 antikoerper, actin related protein 2/3 complex, subunit 2, 34kDa antikoerper, actin related protein 2/3 complex, subunit 2 antikoerper, actin related protein 2/3 complex subunit 2 S homeolog antikoerper, ARPC2 antikoerper, arpc2 antikoerper, Arpc2 antikoerper, arpc2.S antikoerper

Hintergrund:

Background: Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9230079). Seems to contact the mother actin filament (PubMed:9230079). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:29925947). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (PubMed:29925947).

Aliases: Actin related protein 2/3 complex subunit 2 34 kDa antibody, Actin related protein 2/3 complex subunit 2 antibody, Actin-related protein 2/3 complex subunit 2 antibody, ARC 34 antibody, ARC34 antibody, Arp2/3 complex 34 kDa subunit antibody, ARP2/3 protein compex subunit 34 antibody, ARPC 2 antibody, Arpc2 antibody, ARPC2_HUMAN antibody, p34 Arc antibody, p34-ARC antibody, p34Arc antibody, PNAS 139 antibody, PNAS139 antibody, PRO 2446 antibody, PRO2446 antibody

UniProt: O15144

Pathways: RTK Signalweg, Regulation of Actin Filament Polymerization