ROS1 Antikörper (AA 1-320)
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- Target Alle ROS1 Antikörper anzeigen
- ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))
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Bindungsspezifität
- AA 1-320
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Reaktivität
- Arabidopsis thaliana
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ROS1 Antikörper ist unkonjugiert
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Applikation
- ELISA
- Kreuzreaktivität
- Arabidopsis thaliana
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Arabidopsis thaliana Protein ROS1 protein (1-320AA)
- Isotyp
- IgG
- Top Product
- Discover our top product ROS1 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))
- Andere Bezeichnung
- ROS1 (ROS1 Produkte)
- Synonyme
- MCF3 antikoerper, ROS antikoerper, c-ros-1 antikoerper, ROS1C antikoerper, Ros-1 antikoerper, c-ros antikoerper, ROS proto-oncogene 1, receptor tyrosine kinase antikoerper, ROS proto-oncogene 1 , receptor tyrosine kinase antikoerper, Ros1 proto-oncogene antikoerper, ROS1 antikoerper, Ros1 antikoerper
- Hintergrund
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Background: Bifunctional DNA glycosylase/lyase, which excises 5-methylcytosine (5-meC) and 5-hydroxymethylcytosine (5-hmeC), leaving an apyrimidinic (AP) site that is subsequently incised by the lyase activity (PubMed:25240767). Generates 3\'-phosphor-alpha,beta-unsaturated aldehyde (3\'-PUA) as a primary 5-meC excision intermediate (PubMed:25228464). Prevents DNA hypermethylation, specifically in the promoter of otherwise silenced loci. May be involved in DNA repair through its nicking activity on methylated DNA. Binds with similar affinity to both methylated and non-methylated DNA. Highly distributive behavior on DNA substrates containing multiple 5-meC residues. Involved with Pol IV in the remodeling of the 5S rDNA chromatin via DNA methylation modifications during the first days of development post-germination. Participates in UV-B induced- and oxidative DNA damage repair (PubMed:24155752).
Aliases: ROS1 antibody, DML1 antibody, At2g36490 antibody, F1O11.12 antibody, DNA glycosylase/AP lyase ROS1 antibody, EC 4.2.99.18 antibody, DEMETER-like protein 1 antibody, Protein REPRESSOR OF SILENCING 1 antibody, Protein ROS1 antibody
- UniProt
- Q9SJQ6
- Pathways
- RTK Signalweg
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