ROS1 Antikörper
Kurzübersicht für ROS1 Antikörper (ABIN6243980)
Target
Alle ROS1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Aufreinigung
- This antibody is purified through a protein G column, followed by dialysis against PBS.
-
Immunogen
- This ROS1 antibody is generated from a mouse immunized with a recombinant protein of human ROS1.
-
Isotyp
- IgG1 kappa
-
-
anti-C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1) (AA 1945-2222) antibody
ROS1 Reaktivität: Human IHC Wirt: Kaninchen Polyclonal unconjugated
anti-C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1) antibodyKD Validated ROS1 Reaktivität: Human WB, FACS Wirt: Maus Monoclonal 25GB4065 unconjugated
anti-C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1) (AA 1945-2222) antibodyROS1 Reaktivität: Human WB Wirt: Maus Monoclonal C1 unconjugated
anti-C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1) (AA 2231-2347) antibodyROS1 Reaktivität: Human WB, IHC (p), FACS Wirt: Kaninchen Polyclonal unconjugated
anti-C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1) (AA 1744-1777), (C-Term) antibodyROS1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB50575 unconjugated
anti-C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1) (C-Term) antibodyROS1 Reaktivität: Human, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
anti-C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1) (AA 79-248) antibodyROS1 Reaktivität: Human ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
-
-
Applikationshinweise
- IHC: 1:250. WB: 1:4000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C,-20 °C
-
Haltbarkeit
- 6 months
-
-
- ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))
-
Andere Bezeichnung
- ROS1
-
Hintergrund
- Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. Mediates the phosphorylation and the activation of VAV3, a guanine nucleotide exchange factor regulating cell morphology. May activate other downstream signaling proteins including AKT1, MAPK1, MAPK3, IRS1 and PLCG2.
-
Molekulargewicht
- 263915
-
UniProt
- P08922
-
Pathways
- RTK Signalweg
Target
-
