Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

ROS1 Antikörper

ROS1 Reaktivität: Human WB Wirt: Maus Monoclonal 1843CT776-78-21 unconjugated
Produktnummer ABIN6243980
  • Target Alle ROS1 Antikörper anzeigen
    ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))
    Reaktivität
    • 43
    • 28
    • 25
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 50
    • 4
    • 1
    Maus
    Klonalität
    • 50
    • 5
    Monoklonal
    Konjugat
    • 23
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ROS1 Antikörper ist unkonjugiert
    Applikation
    • 33
    • 20
    • 14
    • 8
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    Immunogen
    This ROS1 antibody is generated from a mouse immunized with a recombinant protein of human ROS1.
    Klon
    1843CT776-78-21
    Isotyp
    IgG1 kappa
  • Applikationshinweise
    IHC: 1:250. WB: 1:4000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Target
    ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))
    Andere Bezeichnung
    ROS1 (ROS1 Produkte)
    Synonyme
    MCF3 antikoerper, ROS antikoerper, c-ros-1 antikoerper, ROS1C antikoerper, Ros-1 antikoerper, c-ros antikoerper, ROS proto-oncogene 1, receptor tyrosine kinase antikoerper, ROS proto-oncogene 1 , receptor tyrosine kinase antikoerper, Ros1 proto-oncogene antikoerper, ROS1 antikoerper, Ros1 antikoerper
    Hintergrund
    Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. Mediates the phosphorylation and the activation of VAV3, a guanine nucleotide exchange factor regulating cell morphology. May activate other downstream signaling proteins including AKT1, MAPK1, MAPK3, IRS1 and PLCG2.
    Molekulargewicht
    263915
    UniProt
    P08922
    Pathways
    RTK Signalweg
Sie sind hier:
Kundenservice