BMX Antikörper (pTyr566)

Produktnummer ABIN7139101

Produktdetails anti-BMX Antikörper

Target: BMX (BMX Non-Receptor Tyrosine Kinase (BMX))

Bindungsspezifität: pTyr566

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BMX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Human, Maus

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of Tyrosine566 (D-Q-Y(p)-V-S) derived from Human ETK.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:1000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu BMX

Target: BMX (BMX Non-Receptor Tyrosine Kinase (BMX))

Andere Bezeichnung: BMX (BMX Produkte)

Synonyme: BMX antikoerper, ETK antikoerper, PSCTK2 antikoerper, PSCTK3 antikoerper, Etk antikoerper, Etk/Bmx antikoerper, Tyro8 antikoerper, RGD1565643 antikoerper, BMX non-receptor tyrosine kinase antikoerper, BMX antikoerper, bmx antikoerper, Bmx antikoerper

Hintergrund:

Background:

Non-receptor tyrosine kinase that plays central but diverse modulatory roles in various signaling processes involved in the regulation of actin reorganization, cell migration, cell proliferation and survival, cell adhesion, and apoptosis. Participates in signal transduction stimulated by growth factor receptors, cytokine receptors, G-protein coupled receptors, antigen receptors and integrins. Induces tyrosine phosphorylation of BCAR1 in response to integrin regulation. Activation of BMX by integrins is mediated by PTK2/FAK1, a key mediator of integrin signaling events leading to the regulation of actin cytoskeleton and cell motility.

Zhang R, et al. (2003) J Biol Chem 278, 51267-76
Tsai YT, et al. (2000) Mol Cell Biol 20, 2043-54

Aliases: Bmx antibody, BMX non receptor tyrosine kinase antibody, BMX_HUMAN antibody, BONE MARROW KINASE, X-LINKED antibody, Bone marrow tyrosine kinase gene in chromosome X protein antibody, Cytoplasmic tyrosine protein kinase BMX antibody, Cytoplasmic tyrosine-protein kinase BMX antibody, Epithelial and endothelial tyrosine kinase antibody, ETK antibody, NKT38 antibody, NTK 38 antibody, NTK38 antibody, Protein tyrosine kinase BMX antibody, PSCTK 2 antibody, PSCTK 3 antibody, PSCTK2 antibody, PSCTK3 antibody

UniProt: P51813