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BMX Antikörper (pTyr566)

BMX Reaktivität: Human, Maus WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6255953
  • Target Alle BMX Antikörper anzeigen
    BMX (BMX Non-Receptor Tyrosine Kinase (BMX))
    Bindungsspezifität
    • 19
    • 19
    • 7
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr566
    Reaktivität
    • 59
    • 50
    • 21
    • 5
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 72
    • 3
    Kaninchen
    Klonalität
    • 72
    • 3
    Polyklonal
    Konjugat
    • 42
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser BMX Antikörper ist unkonjugiert
    Applikation
    • 72
    • 36
    • 34
    • 26
    • 26
    • 21
    • 16
    • 7
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    Phospho-BMX (Tyr566) Antibody detects endogenous levels of BMX only when phosphorylated at Tyrosine 566.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Aufreinigung
    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
    Immunogen
    A synthesized peptide derived from human BMX around the phosphorylation site of Tyr566.
    Isotyp
    IgG
    Top Product
    Discover our top product BMX Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    BMX (BMX Non-Receptor Tyrosine Kinase (BMX))
    Andere Bezeichnung
    BMX (BMX Produkte)
    Synonyme
    BMX antikoerper, ETK antikoerper, PSCTK2 antikoerper, PSCTK3 antikoerper, Etk antikoerper, Etk/Bmx antikoerper, Tyro8 antikoerper, RGD1565643 antikoerper, BMX non-receptor tyrosine kinase antikoerper, BMX antikoerper, bmx antikoerper, Bmx antikoerper
    Hintergrund

    Description: Non-receptor tyrosine kinase that plays central but diverse modulatory roles in various signaling processes involved in the regulation of actin reorganization, cell migration, cell proliferation and survival, cell adhesion, and apoptosis. Participates in signal transduction stimulated by growth factor receptors, cytokine receptors, G-protein coupled receptors, antigen receptors and integrins. Induces tyrosine phosphorylation of BCAR1 in response to integrin regulation. Activation of BMX by integrins is mediated by PTK2/FAK1, a key mediator of integrin signaling events leading to the regulation of actin cytoskeleton and cell motility. Plays a critical role in TNF-induced angiogenesis, and implicated in the signaling of TEK and FLT1 receptors, 2 important receptor families essential for angiogenesis. Required for the phosphorylation and activation of STAT3, a transcription factor involved in cell differentiation. Also involved in interleukin-6 (IL6) induced differentiation. Plays also a role in programming adaptive cytoprotection against extracellular stress in different cell systems, salivary epithelial cells, brain endothelial cells, and dermal fibroblasts. May be involved in regulation of endocytosis through its interaction with an endosomal protein RUFY1. May also play a role in the growth and differentiation of hematopoietic cells, as well as in signal transduction in endocardial and arterial endothelial cells.

    Gene: BMX

    Molekulargewicht
    78kDa
    Gen-ID
    660
    UniProt
    P51813
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