ZEB1 Antikörper

Produktnummer ABIN7120942

Produktdetails anti-ZEB1 Antikörper

Target: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZEB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: zinc finger E-box binding homeobox 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:5000, IP: 1:200-1:2000,IHC: 1:500-1:5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu ZEB1

Target: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Andere Bezeichnung: ZEB1 (ZEB1 Produkte)

Synonyme: ZFH/[d]EF1 antikoerper, kheper antikoerper, zeb1 antikoerper, zfhx1 antikoerper, bzp antikoerper, zeb antikoerper, tcf8 antikoerper, areb6 antikoerper, nil2a antikoerper, zfhep antikoerper, nil-2a antikoerper, zfhx1a antikoerper, nil-2-a antikoerper, MGC97552 antikoerper, TCF8 antikoerper, AREB6 antikoerper, BZP antikoerper, DELTAEF1 antikoerper, FECD6 antikoerper, NIL2A antikoerper, PPCD3 antikoerper, ZFHEP antikoerper, ZFHX1A antikoerper, 3110032K11Rik antikoerper, MEB1 antikoerper, Nil2 antikoerper, TCF-8 antikoerper, Tcf18 antikoerper, Tcf8 antikoerper, Tw antikoerper, ZEB antikoerper, Zfhep antikoerper, Zfhx1a antikoerper, Zfx1a antikoerper, Zfx1ha antikoerper, [delta]EF1 antikoerper, deltaEF1 antikoerper, deltaef1 antikoerper, fecd6 antikoerper, zinc finger E-box binding homeobox 1b antikoerper, zinc finger E-box binding homeobox 1 antikoerper, zinc finger E-box binding homeobox 1 S homeolog antikoerper, zeb1b antikoerper, zeb1 antikoerper, ZEB1 antikoerper, Zeb1 antikoerper, zeb1.S antikoerper

Hintergrund: Synonyms:AREB6, BZP, DELTA EF1, delta EF1, Negative regulator of IL2, NIL 2 A, NIL 2 A zinc finger protein, NIL 2A, NIL2A, TCF 8, TCF8, Transcription factor 8, ZEB, ZEB1, ZFHEP, ZFHX1A Background:Acts as a transcriptional repressor. Inhibits interleukin-2(IL-2) gene expression. Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition(EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. Positively regulates neuronal differentiation. Represses RCOR1 transcription activation during neurogenesis. Represses transcription by binding to the E box(5'-CANNTG-3'). Promotes tumorigenicity by repressing stemness-inhibiting microRNAs. The calculated molecular weight of ZEB1 is 124 kDa, but the post phosphorylation of protein is about 190-210 kDa. This is a rabbit polyclonal antibody raised against part of the full length of ZEB1 of human.

Molekulargewicht: 210 kDa

Gen-ID: 6935

UniProt: P37275

Pathways: Regulation of Muscle Cell Differentiation