ZEB1 Antikörper (AA 1-260)
Kurzübersicht für ZEB1 Antikörper (AA 1-260) (ABIN6150422)
Target
Alle ZEB1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-260
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Sequenz
- MADGPRCKRR KQANPRRNNV TNYNTVVETN SDSDDEDKLH IVEEESVTDA ADCEGVPEDD LPTDQTVLPG RSSEREGNAK NCWEDDTGKE GQEILGPEAQ ADEAGCTVKD DECESDAENE QNHDPNVEEF LQQQDTAVIF PEAPEEDQRQ GTPEASGHDE NGTPDAFSQL LTCPYCDRGY KRFTSLKEHI KYRHEKNEDN FSCSLCSYTF AYRTQLERHM TSHKSGRDQR HVTQSGCNRK FKCTECGKAF KYKHHLKEHL
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ZEB1 (NP_001167567.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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: "NatD promotes lung cancer progression by preventing histone H4 serine phosphorylation to activate Slug expression." in: Nature communications, Vol. 8, Issue 1, pp. 928, (2018) (PubMed).
: "LncRNA UCA1 sponges miR-204-5p to promote migration, invasion and epithelial-mesenchymal transition of glioma cells via upregulation of ZEB1." in: Pathology, research and practice, Vol. 214, Issue 9, pp. 1474-1481, (2018) (PubMed).
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- ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))
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Andere Bezeichnung
- ZEB1
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Hintergrund
- This gene encodes a zinc finger transcription factor. The encoded protein likely plays a role in transcriptional repression of interleukin 2. Mutations in this gene have been associated with posterior polymorphous corneal dystrophy-3 and late-onset Fuchs endothelial corneal dystrophy. Alternatively spliced transcript variants encoding different isoforms have been described.,ZEB1,AREB6,BZP,DELTAEF1,FECD6,NIL2A,PPCD3,TCF8,ZFHEP,ZFHX1A,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Wnt/β-Catenin Signaling Pathway,ZEB1
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Molekulargewicht
- 116 kDa/122 kDa/124 kDa
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Gen-ID
- 6935
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UniProt
- P37275
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Pathways
- Regulation of Muscle Cell Differentiation
Target
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