ZEB1 Antikörper (N-Term)

Produktnummer ABIN6972920

Produktdetails anti-ZEB1 Antikörper

Target: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZEB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktmerkmale: ZEB1 (Zinc finger E-box-binding homeobox 1, NIL-2-A zinc finger protein Negative regulator of IL2, NIL-2-A, Transcription factor 8, TCF-8) is a POU domain DNA-binding transcriptional regulator that inhibits the expression of E-cadherin and other epithelial genes central to adhesion and epithelial polarity. ZEB1 induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. ZEB1 positively regulates neuronal differentiation and it represses RCOR1 transcription activation during neurogenesis. Defects in ZEB1 are the cause of posterior polymorphous corneal dystrophy type 3 (PPCD3). ZEB1 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Immunoprecipitation and Western blot, it has been shown to react with Human samples.

Aufreinigung: Affinity Purified

Immunogen: This ZEB1 antibody was raised against a peptide derived from the N-terminal region of human ZEB1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Details zu ZEB1

Target: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Andere Bezeichnung: ZEB1 (ZEB1 Produkte)

Synonyme: ZFH/[d]EF1 antikoerper, kheper antikoerper, zeb1 antikoerper, zfhx1 antikoerper, bzp antikoerper, zeb antikoerper, tcf8 antikoerper, areb6 antikoerper, nil2a antikoerper, zfhep antikoerper, nil-2a antikoerper, zfhx1a antikoerper, nil-2-a antikoerper, MGC97552 antikoerper, TCF8 antikoerper, AREB6 antikoerper, BZP antikoerper, DELTAEF1 antikoerper, FECD6 antikoerper, NIL2A antikoerper, PPCD3 antikoerper, ZFHEP antikoerper, ZFHX1A antikoerper, 3110032K11Rik antikoerper, MEB1 antikoerper, Nil2 antikoerper, TCF-8 antikoerper, Tcf18 antikoerper, Tcf8 antikoerper, Tw antikoerper, ZEB antikoerper, Zfhep antikoerper, Zfhx1a antikoerper, Zfx1a antikoerper, Zfx1ha antikoerper, [delta]EF1 antikoerper, deltaEF1 antikoerper, deltaef1 antikoerper, fecd6 antikoerper, zinc finger E-box binding homeobox 1b antikoerper, zinc finger E-box binding homeobox 1 antikoerper, zinc finger E-box binding homeobox 1 S homeolog antikoerper, zeb1b antikoerper, zeb1 antikoerper, ZEB1 antikoerper, Zeb1 antikoerper, zeb1.S antikoerper

Molekulargewicht: 200 kDa

NCBI Accession: NP_110378

Pathways: Regulation of Muscle Cell Differentiation