NEIL3 Antikörper

Produktnummer ABIN7116771

Produktdetails anti-NEIL3 Antikörper

Target: NEIL3 (Nei Endonuclease VIII-Like 3 (NEIL3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NEIL3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: nei endonuclease VIII-like 3(E. coli)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu NEIL3

Target: NEIL3 (Nei Endonuclease VIII-Like 3 (NEIL3))

Andere Bezeichnung: NEIL3 (NEIL3 Produkte)

Synonyme: RGD1310562 antikoerper, NEIL3 antikoerper, zgc:103553 antikoerper, neil3 antikoerper, MAC12.12 antikoerper, MAC12_12 antikoerper, FGP2 antikoerper, FPG2 antikoerper, NEI3 antikoerper, hFPG2 antikoerper, hNEI3 antikoerper, AI449477 antikoerper, BC034753 antikoerper, C85903 antikoerper, nei-like DNA glycosylase 3 antikoerper, nei like DNA glycosylase 3 antikoerper, GRF zinc finger / Zinc knuckle protein antikoerper, nei-like DNA glycosylase 3 L homeolog antikoerper, nei like 3 (E. coli) antikoerper, Neil3 antikoerper, NEIL3 antikoerper, neil3 antikoerper, AT5G13920 antikoerper, neil3.L antikoerper

Hintergrund: Synonyms: Background:DNA glycosylase which prefers single-stranded DNA(ssDNA), or partially ssDNA structures such as bubble and fork structures, to double-stranded DNA(dsDNA). In vitro, displays strong glycosylase activity towards the hydantoin lesions spiroiminodihydantoin(Sp) and guanidinohydantoin(Gh) in both ssDNA and dsDNA, also recognizes FapyA, FapyG, 5-OHU, 5-OHC, 5-OHMH, Tg and 8-oxoA lesions in ssDNA. No activity on 8-oxoG detected. Also shows weak DNA-(apurinic or apyrimidinic site) lyase activity. In vivo, appears to be the primary enzyme involved in removing Sp and Gh from ssDNA in neonatal tissues. Seems to be an important facilitator of cell proliferation in certain populations, for example neural stem/progenitor cells and tumor cells, suggesting a role in replication-associated DNA repair.

Molekulargewicht: 62-68 kDa

Gen-ID: 55247

UniProt: Q8TAT5

Pathways: DNA Reparatur