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Claspin Antikörper

CLSPN Reaktivität: Human WB, IP, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7112861
  • Target Alle Claspin (CLSPN) Antikörper anzeigen
    Claspin (CLSPN)
    Reaktivität
    • 15
    • 1
    • 1
    Human
    Wirt
    • 15
    Kaninchen
    Klonalität
    • 15
    Polyklonal
    Konjugat
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Claspin Antikörper ist unkonjugiert
    Applikation
    • 8
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), ELISA, Immunofluorescence (IF)
    Aufreinigung
    Immunogen affinity purified
    Reinheit
    ≥95 % as determined by SDS-PAGE
    Immunogen
    claspin homolog(Xenopus laevis)
    Isotyp
    IgG
    Top Product
    Discover our top product CLSPN Primärantikörper
  • Applikationshinweise
    WB: 1:200-1:1000, IP: 1:500-1:2000, IF: 1:20-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Haltbarkeit
    12 months
  • Target
    Claspin (CLSPN)
    Andere Bezeichnung
    CLSPN (CLSPN Produkte)
    Synonyme
    CLSPN antikoerper, xClaspin antikoerper, B130025E01 antikoerper, C85083 antikoerper, E130314M08Rik antikoerper, claspin antikoerper, claspin S homeolog antikoerper, Clspn antikoerper, CLSPN antikoerper, clspn antikoerper, clspn.S antikoerper
    Hintergrund
    Synonyms: Background:Required for checkpoint mediated cell cycle arrest in response to inhibition of DNA replication or to DNA damage induced by both ionizing and UV irradiation. Adapter protein which binds to BRCA1 and the checkpoint kinase CHEK1 and facilitates the ATR-dependent phosphorylation of both proteins. Can also bind specifically to branched DNA structures and may associate with S-phase chromatin following formation of the pre-replication complex(pre-RC). This may indicate a role for this protein as a sensor which monitors the integrity of DNA replication forks.
    Molekulargewicht
    240 kDa
    Gen-ID
    63967
    UniProt
    Q9HAW4
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