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Claspin Produkte

(Claspin (CLSPN))

Kategorien

The product of this gene is an essential upstream regulator of checkpoint kinase 1 and triggers a checkpoint arrest of the cell cycle in response to replicative stress or DNA damage. The protein is also required for efficient DNA replication during a normal S phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010].

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Ausgewählte Claspin Kategorien

Claspin Antikörper

High quality antibodies with extensive validation data.

Empfohlene Claspin Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IHC
Validierungen
  • (2)
Kat. Nr. ABIN6260859
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (1)
Kat. Nr. ABIN7266402
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
Kat. Nr. ABIN6388311
Menge 100 μL
Datenblatt Datenblatt

Empfohlene Claspin ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method
Validierungen
Kat. Nr. ABIN1126688
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1126689
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Claspin Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3091815
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3136084
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Claspin Produkten

Speroni, Federico, Mansilla, Soria, Gottifredi: "Kinase-independent function of checkpoint kinase 1 (Chk1) in the replication of damaged DNA." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 19, pp. 7344-9, (2012) (PubMed).

Benevolo, Musio, Vocaturo, Donà, Rollo, Terrenato, Carosi, Pescarmona, Vocaturo, Mottolese: "Claspin as a biomarker of human papillomavirus-related high grade lesions of uterine cervix." in: Journal of translational medicine, Vol. 10, pp. 132, (2012) (PubMed).

Guervilly, Renaud, Takata, Rosselli: "USP1 deubiquitinase maintains phosphorylated CHK1 by limiting its DDB1-dependent degradation." in: Human molecular genetics, Vol. 20, Issue 11, pp. 2171-81, (2011) (PubMed).

Despras, Daboussi, Hyrien, Marheineke, Kannouche: "ATR/Chk1 pathway is essential for resumption of DNA synthesis and cell survival in UV-irradiated XP variant cells." in: Human molecular genetics, Vol. 19, Issue 9, pp. 1690-701, (2010) (PubMed).

Castriconi, Daga, Dondero, Zona, Poliani, Melotti, Griffero, Marubbi, Spaziante, Bellora, Moretta, Moretta, Corte, Bottino: "NK cells recognize and kill human glioblastoma cells with stem cell-like properties." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 6, pp. 3530-9, (2009) (PubMed).

Gao, Inuzuka, Korenjak, Tseng, Wu, Wan, Kirschner, Dyson, Wei: "Cdh1 regulates cell cycle through modulating the claspin/Chk1 and the Rb/E2F1 pathways." in: Molecular biology of the cell, Vol. 20, Issue 14, pp. 3305-16, (2009) (PubMed).

Guervilly, Macé-Aimé, Rosselli: "Loss of CHK1 function impedes DNA damage-induced FANCD2 monoubiquitination but normalizes the abnormal G2 arrest in Fanconi anemia." in: Human molecular genetics, Vol. 17, Issue 5, pp. 679-89, (2008) (PubMed).

Yang, Shiotani, Classon, Zou: "Chk1 and Claspin potentiate PCNA ubiquitination." in: Genes & development, Vol. 22, Issue 9, pp. 1147-52, (2008) (PubMed).

Li, Elder, Qin, Park, Liang, Zhao: "Phosphatase type 2A-dependent and -independent pathways for ATR phosphorylation of Chk1." in: The Journal of biological chemistry, Vol. 282, Issue 10, pp. 7287-98, (2007) (PubMed).

Yoshizawa-Sugata, Masai: "Human Tim/Timeless-interacting protein, Tipin, is required for efficient progression of S phase and DNA replication checkpoint." in: The Journal of biological chemistry, Vol. 282, Issue 4, pp. 2729-40, (2007) (PubMed).

Synonyme und alternative Namen zu Claspin

claspin (Clspn), claspin (CLSPN), claspin (clspn), claspin S homeolog (clspn.S), B130025E01, C85083, CLSPN, E130314M08Rik, xClaspin

Bezeichner auf Proteinebene für Claspin

  • claspin homolog (Xenopus laevis)
  • claspin
  • claspin homolog
  • hClaspin
  • xClaspin
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