CD276 Antikörper (AA 29-245) (Biotin)

Produktnummer ABIN7289668

Produktdetails anti-CD276 Antikörper (Biotin)

Target: CD276

Bindungsspezifität: AA 29-245

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CD276 Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Flow Cytometry (FACS)

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Immunogen: Recombinant human  B7H3(Leu29-Pro245) (ABIN6961085) produced by using human HEK293 cells

Klon: DM53

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1/5000-10000,Flow Cyt  1/100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute with deionized water

Buffer: 50 % Glycerol, PBS, pH 7.4, 0.1 % BSA,0.1 % Procline 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Details zu CD276

Target: CD276

Andere Bezeichnung: B7-H3 (CD276 Produkte)

Synonyme: sc:d0645 antikoerper, zgc:158279 antikoerper, 6030411F23Rik antikoerper, AU016588 antikoerper, B7RP-2 antikoerper, B7h3 antikoerper, B7H3 antikoerper, 4Ig-B7-H3 antikoerper, B7-H3 antikoerper, CD276 molecule antikoerper, CD276 molecule S homeolog antikoerper, CD276 antigen antikoerper, Cd276 molecule antikoerper, CD276 antikoerper, cd276.S antikoerper, cd276 antikoerper, Cd276 antikoerper

Hintergrund: Synonyms:B7-H3, CD276, B7 homolog 3, B7H3
Description:The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 57 kDa

Gen-ID: 80381

UniProt: Q5ZPR3

Pathways: Cancer Immune Checkpoints