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KDM4B Antikörper

KDM4B Reaktivität: Human, Maus IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7261778
  • Target Alle KDM4B Antikörper anzeigen
    KDM4B (Lysine (K)-Specific Demethylase 4B (KDM4B))
    Reaktivität
    • 89
    • 17
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 86
    • 4
    Kaninchen
    Klonalität
    • 87
    • 3
    Polyklonal
    Konjugat
    • 34
    • 11
    • 10
    • 10
    • 10
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KDM4B Antikörper ist unkonjugiert
    Applikation
    • 65
    • 65
    • 21
    • 19
    • 19
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Immunofluorescence (IF)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human KDM4B (NP_055830.1).
    Isotyp
    IgG
    Top Product
    Discover our top product KDM4B Primärantikörper
  • Applikationshinweise
    IF 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    KDM4B (Lysine (K)-Specific Demethylase 4B (KDM4B))
    Andere Bezeichnung
    KDM4B (KDM4B Produkte)
    Synonyme
    KDM4B antikoerper, JMJD2B antikoerper, jmjd2b antikoerper, si:ch211-124a3.4 antikoerper, TDRD14B antikoerper, 4732474L06Rik antikoerper, Jmjd2b antikoerper, mKIAA0876 antikoerper, lysine demethylase 4B antikoerper, lysine (K)-specific demethylase 4B antikoerper, KDM4B antikoerper, kdm4b antikoerper, Kdm4b antikoerper
    Hintergrund
    JMJD2B (JmjC domain-containing histone demethylation protein 3A) is a 1,064 amino acid protein encoded by the human gene JMJD2B. JMJD2B belongs to the JMJD2B histone demethylase family and contains one JmjC domain, one JmjN domain, two PHD-type zinc fingers and two Tudor domains. The two Tudor domains recognize and bind methylated histones and have an interdigitated structure, the unusual fold is required for its ability to bind methylated histone tails. JMJD2B is a histone demethylase that specifically demethylates Lys 9 residues of Histone H3, thereby playing a role in histone code. It does not demethylate Histone H3 Lys 4, H3 Lys 27, H3 Lys 36 or H4 Lys 20, however, and is only able to demethylate trimethylated H3 Lys-9 and has weaker activity than JMJD2A, JMJD2C and JMJD2D. JMJD2B demethyl-ation of Lysine residues will generate formaldehyde and succinate. JMJD2B is a ubiquitously expressed nuclear protein.
    Gen-ID
    23030
    UniProt
    O94953
    Pathways
    Warburg Effekt
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