PDHA1 Antikörper

Produktnummer ABIN7259915

Produktdetails anti-PDHA1 Antikörper

Target: PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDHA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human PDHA1 (NP_000275.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PDHA1

Target: PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))

Andere Bezeichnung: PDHA1 (PDHA1 Produkte)

Synonyme: PDHA antikoerper, PDHCE1A antikoerper, PHE1A antikoerper, Pdha-1 antikoerper, pdha antikoerper, phe1a antikoerper, pdhce1a antikoerper, im:6895726 antikoerper, pdha1 antikoerper, wu:fd18b01 antikoerper, wu:fo96f03 antikoerper, zgc:73271 antikoerper, zgc:86692 antikoerper, Pdha1 antikoerper, wu:fp73b04 antikoerper, zgc:92705 antikoerper, NI36_05250 antikoerper, pdha1-a antikoerper, pdha1-b antikoerper, pyruvate dehydrogenase E1 alpha 1 subunit antikoerper, pyruvate dehydrogenase E1 alpha 1 antikoerper, pyruvate dehydrogenase (lipoamide) alpha 1 antikoerper, pyruvate dehydrogenase (lipoamide) alpha 1 pseudogene antikoerper, 2-oxo acid dehydrogenase antikoerper, pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha antikoerper, pyruvate dehydrogenase alpha subunit protein antikoerper, pyruvate dehydrogenase (acetyl-transferring) protein, alpha subunit antikoerper, precursor of dehydrogenase pyruvate dehydrogenase E1 component alpha subunit antikoerper, pyruvate dehydrogenase antikoerper, pyruvate dehydrogenase E1 alpha 1 subunit a antikoerper, pyruvate dehydrogenase E1 alpha 1 subunit b antikoerper, pyruvate dehydrogenase E1 component subunit alpha antikoerper, pyruvate dehydrogenase (lipoamide) alpha 1 S homeolog antikoerper, PDHA1 antikoerper, Pdha1 antikoerper, pdha1 antikoerper, LOC719277 antikoerper, VNG_RS07485 antikoerper, RR_RS04695 antikoerper, pdhA1 antikoerper, pdha1a antikoerper, pdha1b antikoerper, NI36_RS05240 antikoerper, pdha1.S antikoerper

Hintergrund: The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht:

Observed_MW: 45 kDa

Calculated_MW: 40 kDa/43 kDa/44 kDa/47 kDa

Gen-ID: 5160

UniProt: P08559

Pathways: Warburg Effekt