PDHA1 Antikörper (AA 30-390)

Produktnummer ABIN3023697

Produktdetails anti-PDHA1 Antikörper

Target: PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))

Bindungsspezifität: AA 30-390

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDHA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Sequenz: FANDATFEIK KCDLHRLEEG PPVTTVLTRE DGLKYYRMMQ TVRRMELKAD QLYKQKIIRG FCHLCDGQEA CCVGLEAGIN PTDHLITAYR AHGFTFTRGL SVREILAELT GRKGGCAKGK GGSMHMYAKN FYGGNGIVGA QVPLGAGIAL ACKYNGKDEV CLTLYGDGAA NQGQIFEAYN MAALWKLPCI FICENNRYGM GTSVERAAAS TDYYKRGDFI PGLRVDGMDI LCVREATRFA AAYCRSGKGP ILMELQTYRY HGHSMSDPGV SYRTREEIQE VRSKSDPIML LKDRMVNSNL ASVEELKEID VEVRKEIEDA AQFATADPEP PLEELGYHIY SSDPPFEVRG ANQWIKFKSV S

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-390 of human PDHA1 (NP_000275.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:20 - 1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PDHA1

Target: PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))

Andere Bezeichnung: PDHA1 (PDHA1 Produkte)

Synonyme: PDHA antikoerper, PDHCE1A antikoerper, PHE1A antikoerper, Pdha-1 antikoerper, pdha antikoerper, phe1a antikoerper, pdhce1a antikoerper, im:6895726 antikoerper, pdha1 antikoerper, wu:fd18b01 antikoerper, wu:fo96f03 antikoerper, zgc:73271 antikoerper, zgc:86692 antikoerper, Pdha1 antikoerper, wu:fp73b04 antikoerper, zgc:92705 antikoerper, NI36_05250 antikoerper, pdha1-a antikoerper, pdha1-b antikoerper, pyruvate dehydrogenase E1 alpha 1 subunit antikoerper, pyruvate dehydrogenase E1 alpha 1 antikoerper, pyruvate dehydrogenase (lipoamide) alpha 1 antikoerper, pyruvate dehydrogenase (lipoamide) alpha 1 pseudogene antikoerper, 2-oxo acid dehydrogenase antikoerper, pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha antikoerper, pyruvate dehydrogenase alpha subunit protein antikoerper, pyruvate dehydrogenase (acetyl-transferring) protein, alpha subunit antikoerper, precursor of dehydrogenase pyruvate dehydrogenase E1 component alpha subunit antikoerper, pyruvate dehydrogenase antikoerper, pyruvate dehydrogenase E1 alpha 1 subunit a antikoerper, pyruvate dehydrogenase E1 alpha 1 subunit b antikoerper, pyruvate dehydrogenase E1 component subunit alpha antikoerper, pyruvate dehydrogenase (lipoamide) alpha 1 S homeolog antikoerper, PDHA1 antikoerper, Pdha1 antikoerper, pdha1 antikoerper, LOC719277 antikoerper, VNG_RS07485 antikoerper, RR_RS04695 antikoerper, pdhA1 antikoerper, pdha1a antikoerper, pdha1b antikoerper, NI36_RS05240 antikoerper, pdha1.S antikoerper

Hintergrund: The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,PDHA1,PDHA,PDHAD,PDHCE1A,PHE1A,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Carbohydrate metabolism,Warburg Effect,PDHA1

Molekulargewicht: 40 kDa/43 kDa/44 kDa/47 kDa

Gen-ID: 5160

UniProt: P08559

Pathways: Warburg Effekt