RIC8A Antikörper

Produktnummer ABIN7007364

Produktdetails anti-RIC8A Antikörper

Target: RIC8A (Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RIC8A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human RIC8A (NP_001273063.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu RIC8A

Target: RIC8A (Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A))

Andere Bezeichnung: RIC8A (RIC8A Produkte)

Synonyme: RIC8 antikoerper, AI114950 antikoerper, RIC-8 antikoerper, Ric8a antikoerper, Ric-8A antikoerper, Ric8 antikoerper, ric-8 antikoerper, ric8 antikoerper, synembryn antikoerper, xtric-8 antikoerper, zgc:92294 antikoerper, Syn antikoerper, ric8a antikoerper, ric8ab antikoerper, CG15797 antikoerper, DmRic8 antikoerper, Dmel\\CG15797 antikoerper, Ric-8 antikoerper, l(1)G0397 antikoerper, ric-8a antikoerper, ricc8aa antikoerper, fj97c10 antikoerper, synbl antikoerper, wu:fj97c10 antikoerper, RIC8 guanine nucleotide exchange factor A antikoerper, microRNA 6743 antikoerper, synembryn-A antikoerper, RIC8 guanine nucleotide exchange factor A L homeolog antikoerper, CG15797 gene product from transcript CG15797-RB antikoerper, synembryn antikoerper, RIC8 guanine nucleotide exchange factor A S homeolog antikoerper, Synembryn antikoerper, RIC8 guanine nucleotide exchange factor B antikoerper, RIC8A antikoerper, Ric8a antikoerper, ric8a antikoerper, MIR6743 antikoerper, Tsp_08768 antikoerper, ric8a.L antikoerper, LOC411841 antikoerper, ric8a.S antikoerper, ric-8 antikoerper, ric8b antikoerper

Hintergrund: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex (By similarity). Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation.

Molekulargewicht:

Observed_MW: 60 kDa

Calculated_MW: 58 kDa/59 kDa/60 kDa

Gen-ID: 60626

UniProt: Q9NPQ8

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Asymmetric Protein Localization