RIC8A Antikörper (C-Term)
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- Target Alle RIC8A Antikörper anzeigen
- RIC8A (Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RIC8A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Ratte (Rattus), Rind (Kuh)
- Kreuzreaktivität (Details)
- Rat (100 %), Bovine (100 %)
- Produktmerkmale
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Rabbit Polyclonal antibody to RIC8A (resistance to inhibitors of cholinesterase 8 homolog A (C. elegans))
RIC8A antibody - Aufreinigung
- Purified by antigen-affinity chromatography.
- Immunogen
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human RIC8A. The exact sequence is proprietary.
- Isotyp
- IgG
- Top Product
- Discover our top product RIC8A Primärantikörper
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- Applikationshinweise
- Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
- Kommentare
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Positive Control: A431 , H1299 , HeLa , HepG2 , Raji
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.85 mg/mL
- Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- Konservierungsmittel
- Thimerosal (Merthiolate)
- Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- RIC8A (Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A))
- Andere Bezeichnung
- RIC8A (RIC8A Produkte)
- Synonyme
- RIC8 antikoerper, AI114950 antikoerper, RIC-8 antikoerper, Ric8a antikoerper, Ric-8A antikoerper, Ric8 antikoerper, ric-8 antikoerper, ric8 antikoerper, synembryn antikoerper, xtric-8 antikoerper, zgc:92294 antikoerper, Syn antikoerper, ric8a antikoerper, ric8ab antikoerper, CG15797 antikoerper, DmRic8 antikoerper, Dmel\\CG15797 antikoerper, Ric-8 antikoerper, l(1)G0397 antikoerper, ric-8a antikoerper, ricc8aa antikoerper, fj97c10 antikoerper, synbl antikoerper, wu:fj97c10 antikoerper, RIC8 guanine nucleotide exchange factor A antikoerper, microRNA 6743 antikoerper, synembryn-A antikoerper, RIC8 guanine nucleotide exchange factor A L homeolog antikoerper, CG15797 gene product from transcript CG15797-RB antikoerper, synembryn antikoerper, RIC8 guanine nucleotide exchange factor A S homeolog antikoerper, Synembryn antikoerper, RIC8 guanine nucleotide exchange factor B antikoerper, RIC8A antikoerper, Ric8a antikoerper, ric8a antikoerper, MIR6743 antikoerper, Tsp_08768 antikoerper, ric8a.L antikoerper, LOC411841 antikoerper, ric8a.S antikoerper, ric-8 antikoerper, ric8b antikoerper
- Hintergrund
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Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex (By similarity). Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation.
- Molekulargewicht
- 60 kDa
- Gen-ID
- 60626
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Asymmetric Protein Localization
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