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AGT Antikörper
AGT
Reaktivität: Human, Ratte, Maus
WB, IHC, ELISA
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN7242469
Produktdetails anti-AGT Antikörper
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Target
Alle AGT Antikörper anzeigen
AGT
(Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))
Reaktivität
Alle Reaktivitäten für AGT Antikörper
Human, Ratte, Maus
Wirt
Alle Wirte für AGT Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für AGT Antikörper
Polyklonal
Konjugat
Alle Konjugate für AGT Antikörper
Dieser AGT Antikörper ist unkonjugiert
Applikation
Alle Applikationen für AGT Antikörper
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
Produktmerkmale
Polyclonal Antibody
Aufreinigung
Affinity purification
Immunogen
Synthetic peptide of human AGT
Isotyp
IgG
Top Product
Discover our top product AGT Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
WB 1:500-1:2000, IHC 1:25-1:100
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
0.3 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Details zu AGT
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Target
AGT
(Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))
Andere Bezeichnung
AGT (AGT Produkte )
Synonyme
ANHU antikoerper, SERPINA8 antikoerper, AI265500 antikoerper, AngI antikoerper, AngII antikoerper, Aogen antikoerper, Serpina8 antikoerper, ANRT antikoerper, Ang antikoerper, PAT antikoerper, wu:fb62f06 antikoerper, wu:fj87b02 antikoerper, zgc:111892 antikoerper, AGT antikoerper, angt antikoerper, ANGT antikoerper, angiotensinogen antikoerper, angiotensinogen (serpin peptidase inhibitor, clade A, member 8) antikoerper, AGT antikoerper, Agt antikoerper, agt antikoerper
Hintergrund
The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
Molekulargewicht
53 kDa
NCBI Accession
NP_000020
UniProt
P01019
Pathways
JAK-STAT Signalweg , ACE Inhibitor Pathway , EGFR Signaling Pathway , Peptide Hormone Metabolism , Regulation of Systemic Arterial Blood Pressure by Hormones , Regulation of Lipid Metabolism by PPARalpha , Protein targeting to Nucleus , Feeding Behaviour , Monocarboxylic Acid Catabolic Process , Dicarboxylic Acid Transport , Positive Regulation of Response to DNA Damage Stimulus , Regulation of long-term Neuronal Synaptic Plasticity
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