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AIM2 Antikörper

AIM2 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7236297
  • Target Alle AIM2 Antikörper anzeigen
    AIM2 (Absent in Melanoma 2 (AIM2))
    Reaktivität
    • 68
    • 24
    • 18
    • 3
    • 2
    • 1
    Human
    Wirt
    • 55
    • 12
    • 2
    Kaninchen
    Klonalität
    • 60
    • 9
    Polyklonal
    Konjugat
    • 38
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser AIM2 Antikörper ist unkonjugiert
    Applikation
    • 63
    • 33
    • 33
    • 22
    • 13
    • 13
    • 12
    • 9
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein of human AIM2
    Isotyp
    IgG
    Top Product
    Discover our top product AIM2 Primärantikörper
  • Applikationshinweise
    IHC 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.8 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    AIM2 (Absent in Melanoma 2 (AIM2))
    Andere Bezeichnung
    AIM2 (AIM2 Produkte)
    Synonyme
    AIM2 antikoerper, PYHIN4 antikoerper, Gm1313 antikoerper, Ifi210 antikoerper, absent in melanoma 2 antikoerper, AIM2 antikoerper, Aim2 antikoerper
    Hintergrund
    Interferon-inducible protein AIM2 (Absent in melanoma 2) is a 343 amino acid protein belonging to the HIN-200 family. Induced by IFN-, AIM2 is thought to act as a tumor suppressor by repressing NFB transcriptional activity. Localized to the nucleus, AIM2 contains one DAPIN domain and one HIN-200 domain. The DAPIN domain is composed mostly of -helixes and is a protein-protein interaction domain capable of binding other DAPIN domains. The HIN-200 domain has been shown to bind directly to DNA, which, along with the binding of another protein ASC, results in the activation of Caspase-1.
    UniProt
    O14862
    Pathways
    Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
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