PTRF Antikörper (C-Term)

Produktnummer ABIN6991834

Produktdetails anti-PTRF Antikörper

Target: PTRF (Polymerase I and Transcript Release Factor (PTRF))

Bindungsspezifität: AA 270-320, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTRF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: At least three isoforms of PTRF are known to exist, this antibody detects all three isoforms. It is predicted to not cross-react with other members of the cavin family.

Aufreinigung: PTRF Antibody is affinity chromatography purified via peptide column.

Immunogen: Rabbit polyclonal PTRF antibody was raised against a 19 amino acid peptide near the carboxy terminus of human PTRF. The immunogen is located within amino acids 270 - 320 of PTRF.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: PTRF antibody can be used for detection of PTRF by Western blot at 0.5 - 1 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PTRF Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: PTRF antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu PTRF

Target: PTRF (Polymerase I and Transcript Release Factor (PTRF))

Andere Bezeichnung: PTRF (PTRF Produkte)

Synonyme: MGC53017 antikoerper, MGC89141 antikoerper, PTRF antikoerper, fd20g07 antikoerper, ptrf antikoerper, wu:fd20g07 antikoerper, zgc:162917 antikoerper, CAVIN antikoerper, CAVIN1 antikoerper, CGL4 antikoerper, cavin-1 antikoerper, 2310075E07Rik antikoerper, AW546441 antikoerper, Cav-p60 antikoerper, Cavin antikoerper, caveolae associated protein 1 L homeolog antikoerper, polymerase I and transcript release factor antikoerper, caveolae associated protein 1 antikoerper, caveolae associated protein 1b antikoerper, caveolae associated 1 antikoerper, cavin1.L antikoerper, PTRF antikoerper, cavin1 antikoerper, CAVIN1 antikoerper, cavin1b antikoerper, Cavin1 antikoerper

Hintergrund: PTRF Antibody: The polymerase I and transcript release factor (PTRF) enables the dissociation of paused ternary polymerase I transcription complexes from the 3' end of pre-rRNA transcripts, regulating rRNA transcription by promoting the dissociation of transcription complexes and the re-initiation of polymerase I on nascent rRNA transcripts. PTRF also localizes to caveolae at the plasma membrane and is thought to play a critical role in the formation of caveolae and the stabilization of caveolins, translocating from caveolae to the cytoplasm after insulin stimulation. PTRF is also thought to modify lipid metabolism and insulin-regulated gene expression. Mutations in this gene result in a disorder characterized by generalized lipodystrophy and muscular dystrophy.

Molekulargewicht: 43 kDa

Gen-ID: 284119

NCBI Accession: NP_036364

UniProt: Q6NZI2