PTRF Produkte
(Polymerase I and Transcript Release Factor (PTRF))
Kategorien
This gene encodes a protein that enables the dissociation of paused ternary polymerase I transcription complexes from the 3' end of pre-rRNA transcripts. This protein regulates rRNA transcription by promoting the dissociation of transcription complexes and the reinitiation of polymerase I on nascent rRNA transcripts. This protein also localizes to caveolae at the plasma membrane and is thought to play a critical role in the formation of caveolae and the stabilization of caveolins. This protein translocates from caveolae to the cytoplasm after insulin stimulation. Caveolae contain truncated forms of this protein and may be the site of phosphorylation-dependent proteolysis. This protein is also thought to modify lipid metabolism and insulin-regulated gene expression. Mutations in this gene result in a disorder characterized by generalized lipodystrophy and muscular dystrophy. [provided by RefSeq, Nov 2009].
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Ausgewählte PTRF Kategorien
PTRF Antikörper
High quality antibodies with extensive validation data.
PTRF ELISA Kits
Reliable ELISA kits for a wide range of species.
PTRF Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PTRF Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Cow, Dog, Horse, Human, Mouse, Rabbit, Rat
Applikation
WB, IHC
Validierungen
- (5)
Kat. Nr.
ABIN2779886
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (1)
- (2)
Kat. Nr.
ABIN391621
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (2)
Kat. Nr.
ABIN567011
Menge
50 μL
Datenblatt
Datenblatt
Empfohlene PTRF ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969451
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6975616
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN5592511
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PTRF Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1316890
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1316889
Menge
25 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3131736
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PTRF Produkten
: "Caveolin-1 scaffolding domain peptide prevents hyperoxia-induced airway remodeling in a neonatal mouse model." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 317, Issue 1, pp. L99-L108, (2019) (PubMed).: "Chloride channel ClC- 2 enhances intestinal epithelial tight junction barrier function via regulation of caveolin-1 and caveolar trafficking of occludin." in: Experimental cell research, Vol. 352, Issue 1, pp. 113-122, (2017) (PubMed).
: "Cavin-1 and Caveolin-1 are both required to support cell proliferation, migration and anchorage-independent cell growth in rhabdomyosarcoma." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 95, Issue 6, pp. 585-602, (2015) (PubMed).
: "Reciprocal modulation of surface expression of annexin A2 in a human umbilical vein endothelial cell-derived cell line by eicosapentaenoic acid and docosahexaenoic acid." in: PLoS ONE, Vol. 9, Issue 1, pp. e85045, (2014) (PubMed).
: "Inflammation, caveolae and CD38-mediated calcium regulation in human airway smooth muscle." in: Biochimica et biophysica acta, Vol. 1843, Issue 2, pp. 346-51, (2013) (PubMed).
: "Quantitative proteomics of caveolin-1-regulated proteins: characterization of polymerase i and transcript release factor/CAVIN-1 IN endothelial cells." in: Molecular & cellular proteomics : MCP, Vol. 9, Issue 10, pp. 2109-24, (2010) (PubMed).
: "SDPR induces membrane curvature and functions in the formation of caveolae." in: Nature cell biology, Vol. 11, Issue 7, pp. 807-14, (2009) (PubMed).
: "MURC/Cavin-4 and cavin family members form tissue-specific caveolar complexes." in: The Journal of cell biology, Vol. 185, Issue 7, pp. 1259-73, (2009) (PubMed).
: "PTRF-Cavin, a conserved cytoplasmic protein required for caveola formation and function." in: Cell, Vol. 132, Issue 1, pp. 113-24, (2008) (PubMed).
Synonyme und alternative Namen zu PTRF
caveolae associated protein 1 L homeolog (cavin1.L), polymerase I and transcript release factor (PTRF), caveolae associated protein 1 (cavin1), caveolae associated protein 1 (CAVIN1), caveolae associated protein 1b (cavin1b), caveolae associated 1 (Cavin1), caveolae associated protein 1 (Cavin1), 2310075E07Rik, AW546441, Cav-p60, CAVIN, Cavin, cavin-1, CAVIN1, CGL4, fd20g07, MGC53017, MGC89141, PTRF, ptrf, wu:fd20g07, zgc:162917Bezeichner auf Proteinebene für PTRF
- polymerase I and transcript release factor
- leucine zipper protein
- leucine-zipper protein
- polymerase I and transcript release factor-like
- RNA polymerase I and transcript release factor
- TTF-I interacting peptide 12
- cavin-1
- cav-p60
- cavin
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