PTRF Antikörper (Internal Region)

Produktnummer ABIN6264525

Produktdetails anti-PTRF Antikörper

Target: PTRF (Polymerase I and Transcript Release Factor (PTRF))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTRF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: PTRF Antibody detects endogenous levels of total PTRF.

Homologie: Pig,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PTRF, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu PTRF

Target: PTRF (Polymerase I and Transcript Release Factor (PTRF))

Andere Bezeichnung: CAVIN1 (PTRF Produkte)

Synonyme: MGC53017 antikoerper, MGC89141 antikoerper, PTRF antikoerper, fd20g07 antikoerper, ptrf antikoerper, wu:fd20g07 antikoerper, zgc:162917 antikoerper, CAVIN antikoerper, CAVIN1 antikoerper, CGL4 antikoerper, cavin-1 antikoerper, 2310075E07Rik antikoerper, AW546441 antikoerper, Cav-p60 antikoerper, Cavin antikoerper, caveolae associated protein 1 L homeolog antikoerper, polymerase I and transcript release factor antikoerper, caveolae associated protein 1 antikoerper, caveolae associated protein 1b antikoerper, caveolae associated 1 antikoerper, cavin1.L antikoerper, PTRF antikoerper, cavin1 antikoerper, CAVIN1 antikoerper, cavin1b antikoerper, Cavin1 antikoerper

Hintergrund:

Description: Plays an important role in caveolae formation and organization. Essential for the formation of caveolae in all tissues (PubMed:18056712, PubMed:18191225, PubMed:19726876). Core component of the CAVIN complex which is essential for recruitment of the complex to the caveolae in presence of calveolin-1 (CAV1). Essential for normal oligomerization of CAV1. Promotes ribosomal transcriptional activity in response to metabolic challenges in the adipocytes and plays an important role in the formation of the ribosomal transcriptional loop. Dissociates transcription complexes paused by DNA-bound TTF1, thereby releasing both RNA polymerase I and pre-RNA from the template (By similarity).

Gene: CAVIN1

Molekulargewicht: 43 kDa

Gen-ID: 284119

UniProt: Q6NZI2