PUM1 Produkte
(Pumilio Homolog 1 (PUM1))
Kategorien
This gene encodes a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. The encoded protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of the encoded protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
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Ausgewählte PUM1 Kategorien
PUM1 Antikörper
High quality antibodies with extensive validation data.
PUM1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PUM1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (3)
Kat. Nr.
ABIN391822
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (2)
Kat. Nr.
ABIN392129
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
IHC, IF
Validierungen
- (2)
Kat. Nr.
ABIN7261958
Menge
200 μL
Datenblatt
Datenblatt
Empfohlene PUM1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3094862
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3136020
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN2730163
Menge
20 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PUM1 Produkten
: "ABCA1 protein enhances Toll-like receptor 4 (TLR4)-stimulated interleukin-10 (IL-10) secretion through protein kinase A (PKA) activation." in: The Journal of biological chemistry, Vol. 287, Issue 48, pp. 40502-12, (2012) (PubMed).: "NF-Y recruits both transcription activator and repressor to modulate tissue- and developmental stage-specific expression of human γ-globin gene." in: PLoS ONE, Vol. 7, Issue 10, pp. e47175, (2012) (PubMed).
: "Mammalian Pumilio 2 regulates dendrite morphogenesis and synaptic function." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 7, pp. 3222-7, (2010) (PubMed).
: "Ribonomic analysis of human Pum1 reveals cis-trans conservation across species despite evolution of diverse mRNA target sets." in: Molecular and cellular biology, Vol. 28, Issue 12, pp. 4093-103, (2008) (PubMed).
: "Polymorphisms of the human PUMILIO2 gene and male sterility." in: Molecular reproduction and development, Vol. 74, Issue 6, pp. 795-9, (2007) (PubMed).
: "Candidate mRNAs interacting with fertility protein PUMILIO2 in the human germ line." in: Reproductive biology, Vol. 6 Suppl 1, pp. 37-42, (2006) (PubMed).
: "High-molecular-mass APOBEC3G complexes restrict Alu retrotransposition." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 42, pp. 15588-93, (2006) (PubMed).
: "Human Pumilio-2 is expressed in embryonic stem cells and germ cells and interacts with DAZ (Deleted in AZoospermia) and DAZ-like proteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 2, pp. 538-43, (2003) (PubMed).
Synonyme und alternative Namen zu PUM1
pumilio RNA-binding family member 1 (pum1), pumilio RNA binding family member 1 (PUM1), pumilio RNA binding family member 1 (pum1), pumilio RNA-binding family member 1 (Pum1), AA517475, DKFZp459K0627, fb96a03, HSPUM, mKIAA0099, PUM1, PUMH, PUMH1, pumilio1, PUML1, Pumm, si:ch211-285e16.1, wu:fb96a03, wu:fb96a08, zgc:63671Bezeichner auf Proteinebene für PUM1
- pumilio homolog 1
- pumilio homolog 1 (Drosophila)
- pumilio-1
- pumilio 1
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