KLRA1 Antikörper (AA 140-190)

Produktnummer ABIN6991052

Produktdetails anti-KLRA1 Antikörper

Target: KLRA1 (Killer Cell Lectin-Like Receptor, Subfamily A, Member 1 (KLRA1))

Bindungsspezifität: AA 140-190

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KLRA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: At least three isoforms of KLRA1 are known to exist, this antibody recognizes only the long isoform.

Aufreinigung: KLRA1 Antibody is affinity chromatography purified via peptide column.

Immunogen: KLRA1 antibody was raised against a 13 amino acid synthetic peptide near the center of human KLRA1. The immunogen is located within amino acids 140 - 190 of KLRA1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: KLRA1 antibody can be used for detection of KLRA1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 4 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: KLRA1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: KLRA1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu KLRA1

Target: KLRA1 (Killer Cell Lectin-Like Receptor, Subfamily A, Member 1 (KLRA1))

Andere Bezeichnung: KLRA1 (KLRA1 Produkte)

Synonyme: Klra2 antikoerper, Ly49i8 antikoerper, A1 antikoerper, Klra22 antikoerper, Ly49a antikoerper, Ly49o<129> antikoerper, Ly49v antikoerper, LY49 antikoerper, KLRA1 antikoerper, Ly49 antikoerper, killer cell lectin-like receptor, subfamily A, member 1 antikoerper, killer cell lectin-like receptor subfamily A, member 1 antikoerper, Klra1 antikoerper, KLRA1 antikoerper, LY49 antikoerper

Hintergrund: KLRA1 Antibody: KLRA1 (also known as Ly49L) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA1 is thought to be an activating receptor, inducing DAP12 phosphorylation in response to antibody-mediated cross-linking of KLRA1 on NK cells.

Gen-ID: 10748