KLRA1 Antikörper (Center)

Produktnummer ABIN783572

Produktdetails anti-KLRA1 Antikörper

Target: KLRA1 (Killer Cell Lectin-Like Receptor, Subfamily A, Member 1 (KLRA1))

Bindungsspezifität: Center

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KLRA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 13 amino acid peptide near the center of human KLRA1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Details zu KLRA1

Target: KLRA1 (Killer Cell Lectin-Like Receptor, Subfamily A, Member 1 (KLRA1))

Andere Bezeichnung: KLRA1 (KLRA1 Produkte)

Synonyme: Klra2 antikoerper, Ly49i8 antikoerper, A1 antikoerper, Klra22 antikoerper, Ly49a antikoerper, Ly49o<129> antikoerper, Ly49v antikoerper, LY49 antikoerper, KLRA1 antikoerper, Ly49 antikoerper, killer cell lectin-like receptor, subfamily A, member 1 antikoerper, killer cell lectin-like receptor subfamily A, member 1 antikoerper, Klra1 antikoerper, KLRA1 antikoerper, LY49 antikoerper

Hintergrund: KLRA1 (also known as Ly49L) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA1 is thought to be an activating receptor, inducing DAP12 phosphorylation in response to antibody-mediated cross-linking of KLRA1 on NK cells. At least three isoforms of KLRA1 are known to exist, this antibody recognizes only the long isoform.Synonyms: KLRA-1, Killer cell lectin-like receptor subfamily A, LY49A, LY49L, Lymphocyte antigen 49a, T lymphocyte antigen A1, member 1

Gen-ID: 10090

UniProt: P20937