TNFSF15 Antikörper (N-Term)

Produktnummer ABIN6990418

Produktdetails anti-TNFSF15 Antikörper

Target: TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))

Bindungsspezifität: AA 60-110, N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNFSF15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: This polyclonal antibody will not cross-react with TL1.

Aufreinigung: TL1A Antibody is affinity chromatography purified via peptide column.

Immunogen: TL1A antibody was raised against a peptide corresponding to 14 amino acids near the amino terminus of human TL1A. The immunogen is located within amino acids 60 - 110 of TL1A.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: TL1A antibody can be used for detection of TL1A by Western blot at 0.5 to 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: TL1A Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: TL1A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu TNFSF15

Target: TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))

Andere Bezeichnung: TL1A (TNFSF15 Produkte)

Synonyme: TTPAL antikoerper, TL1 antikoerper, TL1A antikoerper, VEGI antikoerper, VEGI192A antikoerper, Tl1 antikoerper, Tl1a antikoerper, Vegi antikoerper, tumor necrosis factor superfamily member 15 antikoerper, TNF superfamily member 15 antikoerper, tumor necrosis factor (ligand) superfamily, member 15 antikoerper, TNFSF15 antikoerper, Tnfsf15 antikoerper

Hintergrund: TL1A Antibody: Members in the TNF and its receptor superfamilies regulate immune responses and induce apoptosis. DR3 (also termed Wsl-1, Apo-3, TRAMP, and LARD) is preferentially expressed by T lymphocytes and upregulated during T cell activation. The ligand for DR3 was recently identified and designated TL1A. TL1A also binds decoy receptor DcR3/TR6, which is expressed in several lung and colon carcinomas and in some normal tissues. TL1A induces apoptosis and NF-κ,B activation in DR3 expressing cells, which is antagonized by DcR3. TL1A is upregulated by proinflammatory cytokines TNF and IL-1. TL1A is a longer variant of TL1 (also called VEGI).

Molekulargewicht: Predicted: 28 kDa

Observed: 26 kDa

Gen-ID: 9966

UniProt: O95150

Pathways: Positive Regulation of Endopeptidase Activity, Autophagie