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CD45 Antikörper (AA 1-100)

PTPRC Reaktivität: Human FACS, WB, IHC (p), ELISA, IHC (fro) Wirt: Maus Monoclonal 14A9 unconjugated

Produktnummer ABIN6989429

Datenblatt (PDF)

Target Alle CD45 (PTPRC) Antikörper anzeigen

CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))
Bindungsspezifität
16

16

14

13

12

10

9

7

6

6

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-100
Reaktivität
372

233

88

29

20

16

15

10

7

6

6

6

4

4

3

3

2

1

1

1

1

1

1

1

1

1
Human
Wirt
269

183

137

2

1
Maus
Passende Sekundärantikörper
Klonalität
456

128

1
Monoklonal
Konjugat
173

54

47

47

34

15

14

12

12

11

10

10

8

8

8

6

6

6

6

5

4

4

4

4

4

4

4

4

4

4

4

4

4

3

3

3

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1
Dieser CD45 Antikörper ist unkonjugiert
Applikation
474

191

155

128

102

59

48

40

38

27

17

15

14

13

11

7

5

5

5

4

3

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1
Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität

Human

Aufreinigung

Purified by Protein G.

Immunogen

Recombinant human CD45

Klon

14A9

Isotyp

IgG1

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anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (C-Term) antibody
PTPRC Reaktivität: Human, Maus, Ratte, Hund, Huhn, Rind (Kuh), Cat, Kaninchen, Schaf, Schwein, Meerschweinchen, Ziege, Pferd, Affe, Avian, Esel, Hamster WB Wirt: Ziege Polyclonal unconjugated

anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 378-577) antibody
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anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 431-577) antibody
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PTPRC Reaktivität: Human IHC, WB, ELISA Wirt: Maus Monoclonal 5D3A3 unconjugated

Applikationshinweise

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit

12 months
Target

CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))

Andere Bezeichnung

CD45 (PTPRC Produkte)

Synonyme

PTPRC antikoerper, si:dkeyp-47c5.1 antikoerper, B220 antikoerper, CD45 antikoerper, CD45R antikoerper, GP180 antikoerper, L-CA antikoerper, LCA antikoerper, LY5 antikoerper, T200 antikoerper, Cd45 antikoerper, Ly-5 antikoerper, Lyt-4 antikoerper, loc antikoerper, Lca antikoerper, RT7 antikoerper, cd45 antikoerper, protein tyrosine phosphatase, receptor type C antikoerper, protein tyrosine phosphatase, receptor type, C antikoerper, receptor-type tyrosine-protein phosphatase C antikoerper, PTPRC antikoerper, ptprc antikoerper, LOC100074271 antikoerper, Ptprc antikoerper

Hintergrund

Synonyms: B220, CD 45, CD-45, CD45, cd45 antigen, ec3.1.3.48, CD45R, GP180, GP180, GP 180, L CA, LCA, L-CA, Leukocyte common antigen, LY5, Ly-5 glycoprotein, Protein tyrosine phosphatase receptor type C, Protein tyrosine phosphatase receptor type c polypeptide, protein tyrosine phosphatase, receptor type, C, Receptor-type tyrosine-protein phosphatase C, PTPRC, PTPRC_HUMAN, SCID due to PTPRC deficiency, T200, T200 glycoprotein, T200 leukocyte common antigen, Human homolog of severe combined immunodeficiency due to PTPRC deficiency.
Background: Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity.

Gen-ID

5788

UniProt

P08575

Pathways

T-Zell Rezeptor Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, BCR Signaling