CD40 Ligand Antikörper (PE)

Produktnummer ABIN6961542

Produktdetails anti-CD40 Ligand Antikörper (PE)

Target: CD40 Ligand (CD40LG)

Reaktivität: Maus

Wirt: Armenischer Hamster

Klonalität: Monoklonal

Konjugat: Dieser CD40 Ligand Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Aufreinigung: This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. It is recommended to store the product undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.

Klon: MR1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: This antibody preparation has been quality-tested for flow cytometry using mouse spleen cells, or an appropriate cell type (where indicated). The amount of antibody required for optimal staining of a cell sample should be determined empirically in your system.

Kommentare:

0.2 mg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 10 mM NaH2PO4, 150 mM NaCl, 0.09 % Sodium azide, 0.1 % gelatin, pH 7.2

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C protected from light

Haltbarkeit: 12 months

Details zu CD40 Ligand

Target: CD40 Ligand (CD40LG)

Andere Bezeichnung: CD154 (CD40LG Produkte)

Synonyme: CD154 antikoerper, cd40l antikoerper, CD40L antikoerper, HIGM1 antikoerper, IGM antikoerper, IMD3 antikoerper, T-BAM antikoerper, TNFSF5 antikoerper, TRAP antikoerper, gp39 antikoerper, hCD40L antikoerper, CD40-L antikoerper, Cd40l antikoerper, Ly-62 antikoerper, Ly62 antikoerper, Tnfsf5 antikoerper, CD40 ligand antikoerper, TNF superfamily member 5 antikoerper, CD40LG antikoerper, cd40l antikoerper, Cd40lg antikoerper

Hintergrund: The MR1 antibody is specific for mouse CD154, a 39 kD glycoprotein that is primarily expressed on activated T cells. CD154 (CD40 ligand, gp39) binds to CD40 expressed on antigen presenting cells and mediates important costimulatory functions between these cells. Signals generated via cognate interactions between CD154-CD40 on activated T and B cells are required for T-dependent B cell responses. The MR1 antibody is reported to block interaction of CD154 with CD40.

Gen-ID: 21947

UniProt: P27548

Pathways: NF-kappaB Signalweg, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints