TNFRSF18 Antikörper (FITC)
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- Target Alle TNFRSF18 Antikörper anzeigen
- TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))
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Reaktivität
- Maus
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser TNFRSF18 Antikörper ist konjugiert mit FITC
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Applikation
- Flow Cytometry (FACS)
- Aufreinigung
- This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. It is recommended to store the product undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.
- Klon
- DTA-1
- Isotyp
- IgG2b
- Top Product
- Discover our top product TNFRSF18 Primärantikörper
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- Applikationshinweise
- This antibody preparation has been quality-tested for flow cytometry using mouse spleen cells, or an appropriate cell type (where indi- cated). The amount of antibody required for optimal staining of a cell sample should be determined empirically in your system.
- Kommentare
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0.5 mg/mL
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- 10 mM Tris, 150 mM NaCl, 0.05 % BSA, 0.05 % Sodium azide, pH 8
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- 2-8°C protected from light
- Haltbarkeit
- 12 months
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- Target
- TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))
- Andere Bezeichnung
- CD357 (GITR) (TNFRSF18 Produkte)
- Synonyme
- GITR antikoerper, TNFRSF18 antikoerper, AITR antikoerper, Gitr antikoerper, CD357 antikoerper, GITR-D antikoerper, TNF receptor superfamily member 18 antikoerper, tumor necrosis factor receptor superfamily, member 18 antikoerper, TNFRSF18 antikoerper, Tnfrsf18 antikoerper
- Hintergrund
- The DTA-1 antibody reacts with mouse CD357, also known as GITR or AITR (in humans), a 66-70 kDa member of the Tumor Necrosis Factor superfamily (TNFRSF18). GITR is primarily found on T cells, and its function may vary depending on the T cell type where it is ex- pressed. GITR is upregulated on activated T cells where it provides co-stimulation, yet GITR may promote the inhibition of CD4+ CD25+ Treg cells, where it is expressed at high levels. GITR ligand (GITRL) is found on B cells, macrophages, dendritic and endothelial cells, and is implicated in regulating both innate and adaptive immune responses.The DTA-1 antibody may be used for analysis of GITR expres- sion on T cells, and is also commonly used in vitro as an agonistic antibody to induce GITR signaling in various assays.
- Gen-ID
- 21936
- UniProt
- O35714
- Pathways
- Cancer Immune Checkpoints
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