TNFRSF18 Antikörper (AA 26-162)

Produktnummer ABIN5684059

Produktdetails anti-TNFRSF18 Antikörper

Target: TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))

Bindungsspezifität: AA 26-162

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TNFRSF18 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Neutralization (Neut)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human TNFRSF18 (AA: extra 26-162) expressed in E. coli.

Klon: 2A7A6

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: 1:200 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Details zu TNFRSF18

Target: TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))

Andere Bezeichnung: TNFRSF18 (TNFRSF18 Produkte)

Synonyme: GITR antikoerper, TNFRSF18 antikoerper, AITR antikoerper, Gitr antikoerper, CD357 antikoerper, GITR-D antikoerper, TNF receptor superfamily member 18 antikoerper, tumor necrosis factor receptor superfamily, member 18 antikoerper, TNFRSF18 antikoerper, Tnfrsf18 antikoerper

Hintergrund:

Description: This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Aliases: AITR, GITR, CD357, GITR-D

Molekulargewicht: 26 kDa

Gen-ID: 8784

HGNC: 84868

Pathways: Cancer Immune Checkpoints