NFKBIE Antikörper

Produktnummer ABIN6944283

Produktdetails anti-NFKBIE Antikörper

Target: NFKBIE (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, epsilon (NFKBIE))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser NFKBIE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A.

Immunogen: Full length protein

Klon: 7A4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu NFKBIE

Target: NFKBIE (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, epsilon (NFKBIE))

Andere Bezeichnung: NFKBIE (NFKBIE Produkte)

Synonyme: NFKBIE antikoerper, IKBE antikoerper, Slc35b2 antikoerper, NFKB inhibitor epsilon antikoerper, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon antikoerper, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon antikoerper, NFKBIE antikoerper, Nfkbie antikoerper

Hintergrund:

Synonyms: NF-kappa-B inhibitor epsilon, I-kappa-B-epsilon, NF-kappa-BIE, IkB-E, IkB-epsilon, IKB epsilon, IkappaBepsilon, NFKBIE, NFKB inhibitor epsilon

Background: The protein encoded by this gene binds to components of NF-kappa-B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF-kappa-B by making it available to translocate to the nucleus. Inhibits DNA-binding of NF-kappa-B p50-p65 and p50-c-Rel complexes.

Gen-ID: 4794

UniProt: O00221

Pathways: NF-kappaB Signalweg, Maintenance of Protein Location