ITPR1 Antikörper

Produktnummer ABIN6943847

Produktdetails anti-ITPR1 Antikörper

Target: ITPR1 (Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser ITPR1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: Human IP3 receptor aa 1770-1900

Klon: 5G10

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store for 1 year at -20°C from date of shipment.

Haltbarkeit: 12 months

Details zu ITPR1

Target: ITPR1 (Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1))

Andere Bezeichnung: ITPR1 (ITPR1 Produkte)

Synonyme: D6Pas2 antikoerper, ENSMUSG00000072853 antikoerper, Gm10429 antikoerper, IP3R1 antikoerper, InsP3R antikoerper, Ip3r antikoerper, Itpr-1 antikoerper, P400 antikoerper, Pcp-1 antikoerper, Pcp1 antikoerper, opt antikoerper, I145TR antikoerper, InsP3R1 antikoerper, INSP3R1 antikoerper, IP3R antikoerper, SCA15 antikoerper, SCA16 antikoerper, SCA29 antikoerper, inositol 1,4,5-trisphosphate receptor type 1 antikoerper, inositol 1,4,5-trisphosphate receptor 1 antikoerper, inositol 1,4,5-trisphosphate receptor, type 1 antikoerper, ITPR1 antikoerper, Itpr1 antikoerper

Hintergrund:

Synonyms: Inositol 1,4,5-trisphosphate receptor type 1, IP3 receptor isoform 1, Type 1 inositol 1,4,5-trisphosphate receptor, IP3R 1, InsP3R1, Type 1 InsP3 receptor, ITPR1, INSP3R1, IP3 Receptor.

Background: Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).

Gen-ID: 3708

UniProt: Q14643

Pathways: Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, Synaptic Membrane, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma