ITPR1 Antikörper (AA 1707-1966)

Produktnummer ABIN7156293

Produktdetails anti-ITPR1 Antikörper

Target: ITPR1 (Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1))

Bindungsspezifität: AA 1707-1966

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ITPR1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Inositol 1,4,5-trisphosphate receptor type 1 protein (1707-1966AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ITPR1

Target: ITPR1 (Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1))

Andere Bezeichnung: ITPR1 (ITPR1 Produkte)

Synonyme: D6Pas2 antikoerper, ENSMUSG00000072853 antikoerper, Gm10429 antikoerper, IP3R1 antikoerper, InsP3R antikoerper, Ip3r antikoerper, Itpr-1 antikoerper, P400 antikoerper, Pcp-1 antikoerper, Pcp1 antikoerper, opt antikoerper, I145TR antikoerper, InsP3R1 antikoerper, INSP3R1 antikoerper, IP3R antikoerper, SCA15 antikoerper, SCA16 antikoerper, SCA29 antikoerper, inositol 1,4,5-trisphosphate receptor type 1 antikoerper, inositol 1,4,5-trisphosphate receptor 1 antikoerper, inositol 1,4,5-trisphosphate receptor, type 1 antikoerper, ITPR1 antikoerper, Itpr1 antikoerper

Hintergrund:

Background: Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate (PubMed:27108797). Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1 (By similarity). Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).

Aliases: 4 antibody, 5-trisphosphate receptor antibody, 5-trisphosphate receptor type 1 antibody, DKFZp313E1334 antibody, DKFZp313N1434 antibody, inositol 1 4 5 triphosphate receptor type 1 antibody, Inositol 1 4 5 trisphosphate Receptor Type 1 antibody, Inositol 1 antibody, InsP3R1 antibody, IP3 antibody, IP3 receptor antibody, IP3 receptor isoform 1 antibody, IP3R 1 antibody, IP3R antibody, IP3R1 antibody, ITPR 1 antibody, Itpr1 antibody, ITPR1_HUMAN antibody, SCA15 antibody, SCA16 antibody, SCA29 antibody, Type 1 inositol 1 4 5 trisphosphate receptor antibody, Type 1 inositol 1 antibody, Type 1 InsP3 receptor antibody

UniProt: Q14643

Pathways: Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, Synaptic Membrane, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma